nephrogenic diabetes insipidus

DEFINITION:

A syndrome of polyuria and hyposthenuria caused by the failure of the renal tubules to reabsorb water in response to antidiuretic hormone, without disturbance in the renal filtration and solute excretion rates; the condition does not respond to exogenous vasopressin. It may be inherited as a rare X-linked trait or be acquired as a result of drug therapy or systemic disease.

NDI

DEFINITION:

Nephrogenic diabetes insipidus.

challenge

DEFINITION:

1. To administer a chemical substance to a patient for observation of whether the normal physiological response occurs.

2. In immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.

3. The administration of such a chemical or antigen in order to asses for a reponse. Called also "challenge test," "provocative test," and "provocation."

4. To order to halt and prove identify.

5. To take exception to; dispute.

6. To issue an invitation to compete against one, especially in single combat; dare, defy.

7. A stimulating or interesting task or problem.

8. A summons to a duel.

9. An invitation to compete in a sport.

10. A calling into question.

11. An exception taken to a juror.

12. A sentry's command to halt and prove identify.

NDI

DEFINITION:

Nephrogenic diabetes insipidus.

aetiology

DEFINITION:

Alternate spelling for etiology.

presented

DEFINITION:

Having appeared or shown, as having appeared first at the os uteri (said of a fetus), or having appeared for examination, treatment, etc. (said of a patient).

electrolyte

DEFINITION:

A substance that separates into ions when fused or in solution, and thus becomes capable of conducting electricity; an ionic solute.

post-operative

DEFINITION:

Occurring after a surgical operation.

aquaporin channels

DEFINITION:

See aquaporin water channels.

nephrogenic diabetes insipidus

DEFINITION:

A syndrome of polyuria and hyposthenuria caused by the failure of the renal tubules to reabsorb water in response to antidiuretic hormone, without disturbance in the renal filtration and solute excretion rates; the condition does not respond to exogenous vasopressin. It may be inherited as a rare X-linked trait or be acquired as a result of drug therapy or systemic disease.

aetiology

DEFINITION:

Alternate spelling for etiology.

peculiar

DEFINITION:

1. Belonging exclusively to one person or group.
2. Characteristic, distinctive.
3. Queer, odd.

permission

DEFINITION:

Formal consent; authorization.