My son's male cousin who is 3 years old was just diagnosed with Diabetes Insipidus. They are trying to find out if there is a genetic link. My son who is 21 years old now, has frequent urination, up at least 7 times throughout the night to void. He states

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Topic: Health Care
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Depression, memory lapses and fits of rage are not a direct result of any type of DI. However, they might be an indirect result of dehydration and brain damage caused by DI during infancy. From the other symptoms you describe, your son probably does have some form of DI although it may be partial and less severe than most. Since he has a cousin on his father's side who has documented pituitary DI, your son probably has the same type of DI on a genetic basis. If so, the genetic mutation is unique since neither of the brothers with affected sons has obvious signs or symptoms of DI. I would recommend that your son be evaluated to determine if he has pituitary DI. If he does, he should start appropriate treatment and, along with his cousin and other relatives, have a genetic analysis to try to identify or at least localize the mutation responsible.