Currently an Assistant Professor in the Department of Molecular and Medical Genetics at the Oregon Health Sciences University in Portland, Oregon, Dr. Wildin first became involved with Nephrogenic Diabetes Insipidus while doing his residency at the University of Washington in Seattle in 1987. He was looking for a new project and had an interest in NDI as he had seen patients with the disorder. Access to NDI DNA samples through the U. of W. genetics department, coupled with the new research avenues opened by Dr. Birnbaumer's newly cloned cDNA V2 receptor drew him to the exploration of NDI. What started as a short term project has grown to be a major focus of Dr. Wildin's genetic work.
Oregon Health Sciences University
Dr. Wildin feels the future holds promise for NDI patients. As more is learned about the structure of the protein receptors the possibility for developing more effective drug therapies increases. While a cure still remains elusive, it may be possible, in the next 10 years, to have the tools to offer families known to carry NDI-causing genetic mutations the option of in vitro fertilization screening to select healthy embryos for implantation.
Born in San Antonio, Texas, Dr. Wildin spent most of his childhood in that state. His father was in the air force and the family spent three years abroad in Libya and Germany. He received his undergraduate degree (B.S. in Life Sciences) OHSUfrom Massachusetts Institute of Technology and it was there that his interest in biology and genetics developed. With his sights on a career in scientific research he studied medicine at the University of California, San Francisco School of Medicine. He moved to Seattle to complete his Residency in Pediatrics at the University of Washington and continued on at the U. of W. with postgraduate work in Medical Genetics through the National Institute of Child Health and Human Development training program. He moved to Portland in the fall of l996 to assume his current position at O.H.S.U. in Portland. The beauty of the Pacific Northwest does not escape him - Dr. Wildin balances his work in the lab and hospital with time hiking or biking throughout the area.