Prevention of Intracranial Calcifications and Brain Damage Associated with Nephrogenic Diabetes Insipidus [Letter; Comment]
| Title: | Prevention of Intracranial Calcifications and Brain Damage Associated with Nephrogenic Diabetes Insipidus [Letter; Comment] |
|---|---|
| Authors: | Mendonca, Erica V.; Stone, Rosario C.; Rosa, F. Coelho |
| Publisher: | Pediatric Nephrology |
| Date Published: | April 01, 1994 |
| Reference Number: | 108 |
This translation by the NDI Foundation is to assist the lay reader. To provide a clear, accessible interpretation of the original article, we eliminated or simplified some technical detail and complicated scientific language. We concentrated our translation on those aspects of the article dealing directly with NDI. The NDI Foundation thanks the researchers for their work toward understanding and more effectively treating this disorder.
© Copyright NDI Foundation 2007 (JC)
The older brother was not diagnosed or treated for NDI until he was three and a half years old, by which time he already had suffered high blood sodium, bouts of severe dehydration and a delay of his psychomotor development. The younger brother was diagnosed and treated at one month of age.
This study magnifies the importance of early detection and treatment of NDI (which may manifest in the first days of life). For without treatment, the severe bouts of dehydration that can occur could lead to the mental and physical retardation experienced by the older boy.



