inner medullary collecting duct

DEFINITION:

The distal part of the renal tubule, including the loop of Henle, lying within the medulla.

IMCD

DEFINITION:

Inner medullary collecting duct.

site

DEFINITION:

A place, position, or locus.

osmotic water permeability

DEFINITION:

The ability to channel water across a membrane in response to a concentration gradient.

concentration

DEFINITION:

1. Increase in strength by evaporation.

2. The ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.

vasopressin

DEFINITION:

1. One of two octapeptide hormones formed by the neuronal cells of the hypothalamic nuclei and stored in the posterior lobe of the pituitary gland (neurohypophysis), the other being oxytocin. It stimulates the contraction of the muscular tissue of the capillaries and arterioles, raising the blood pressure. It promotes contraction of the intestinal musculature and increases peristalsis, and also exerts some contractile influence on the uterus. It also has a specific effect on the epithelial cells of the distal portion of the uriniferous tubule, augmenting resorption of water independently of solutes, resulting in concentration of urine and dilution of blood serum. Its rate of secretion is regulated chiefly by the osmolarity of the plasma.

2. [USP], A pharmaceutical preparation of the same principle, prepared synthetically or obtained from the posterior pituitary of healthy domestic animals used for food by man; used mainly as an antidiuretic in the treatment of acute or chronic diabetes insipidus, administered intramuscularly as a test of hypothalamo-neurohypophysial-renal function in distinguishing central from nephrogenic diabetes insipidus; it may also be used to stimulate smooth muscle tissue, especially to induce vasoconstriction in the presence of hemorrhage. Called also antidiuretic hormone (ADH).

concentrations

DEFINITION:

1. Increases in strength by evaporation.

2. The ratios of the mass or volume of a solute to the mass or volume of the solution or solvent.

vasopressin

DEFINITION:

1. One of two octapeptide hormones formed by the neuronal cells of the hypothalamic nuclei and stored in the posterior lobe of the pituitary gland (neurohypophysis), the other being oxytocin. It stimulates the contraction of the muscular tissue of the capillaries and arterioles, raising the blood pressure. It promotes contraction of the intestinal musculature and increases peristalsis, and also exerts some contractile influence on the uterus. It also has a specific effect on the epithelial cells of the distal portion of the uriniferous tubule, augmenting resorption of water independently of solutes, resulting in concentration of urine and dilution of blood serum. Its rate of secretion is regulated chiefly by the osmolarity of the plasma.

2. [USP], A pharmaceutical preparation of the same principle, prepared synthetically or obtained from the posterior pituitary of healthy domestic animals used for food by man; used mainly as an antidiuretic in the treatment of acute or chronic diabetes insipidus, administered intramuscularly as a test of hypothalamo-neurohypophysial-renal function in distinguishing central from nephrogenic diabetes insipidus; it may also be used to stimulate smooth muscle tissue, especially to induce vasoconstriction in the presence of hemorrhage. Called also antidiuretic hormone (ADH).

exogenous

DEFINITION:

1. Produced by growth from superficial tissue.

2. Introduced from or produced outside the organism or system; specif: not synthesized within the organism or system.

cyclic GMP

DEFINITION:

Cyclic guanosine monophosphate.

cyclic AMP

DEFINITION:

Cyclic adenosine monophosphate.

affect

DEFINITION:

1. To produce an effect on; influence.

2. The external expression of emotion attached to ideas or mental representations of objects.

vasopressin

DEFINITION:

1. One of two octapeptide hormones formed by the neuronal cells of the hypothalamic nuclei and stored in the posterior lobe of the pituitary gland (neurohypophysis), the other being oxytocin. It stimulates the contraction of the muscular tissue of the capillaries and arterioles, raising the blood pressure. It promotes contraction of the intestinal musculature and increases peristalsis, and also exerts some contractile influence on the uterus. It also has a specific effect on the epithelial cells of the distal portion of the uriniferous tubule, augmenting resorption of water independently of solutes, resulting in concentration of urine and dilution of blood serum. Its rate of secretion is regulated chiefly by the osmolarity of the plasma.

2. [USP], A pharmaceutical preparation of the same principle, prepared synthetically or obtained from the posterior pituitary of healthy domestic animals used for food by man; used mainly as an antidiuretic in the treatment of acute or chronic diabetes insipidus, administered intramuscularly as a test of hypothalamo-neurohypophysial-renal function in distinguishing central from nephrogenic diabetes insipidus; it may also be used to stimulate smooth muscle tissue, especially to induce vasoconstriction in the presence of hemorrhage. Called also antidiuretic hormone (ADH).

cyclic AMP

DEFINITION:

Cyclic adenosine monophosphate.

physiological

DEFINITION:

1. Of or pertaining to physiology.
2. Characteristic of or appropriate to an organism's healthy or normal functioning.
3. Differing in, involving, or affecting physiological factors.

concentrations

DEFINITION:

1. Increases in strength by evaporation.

2. The ratios of the mass or volume of a solute to the mass or volume of the solution or solvent.

inhibition

DEFINITION:

Arrest or restraint of a process.

vasopressin

DEFINITION:

1. One of two octapeptide hormones formed by the neuronal cells of the hypothalamic nuclei and stored in the posterior lobe of the pituitary gland (neurohypophysis), the other being oxytocin. It stimulates the contraction of the muscular tissue of the capillaries and arterioles, raising the blood pressure. It promotes contraction of the intestinal musculature and increases peristalsis, and also exerts some contractile influence on the uterus. It also has a specific effect on the epithelial cells of the distal portion of the uriniferous tubule, augmenting resorption of water independently of solutes, resulting in concentration of urine and dilution of blood serum. Its rate of secretion is regulated chiefly by the osmolarity of the plasma.

2. [USP], A pharmaceutical preparation of the same principle, prepared synthetically or obtained from the posterior pituitary of healthy domestic animals used for food by man; used mainly as an antidiuretic in the treatment of acute or chronic diabetes insipidus, administered intramuscularly as a test of hypothalamo-neurohypophysial-renal function in distinguishing central from nephrogenic diabetes insipidus; it may also be used to stimulate smooth muscle tissue, especially to induce vasoconstriction in the presence of hemorrhage. Called also antidiuretic hormone (ADH).

cyclic GMP

DEFINITION:

Cyclic guanosine monophosphate.

messenger

DEFINITION:

An information carrier, such as a hormone or an electrical impulse.

site

DEFINITION:

A place, position, or locus.

distal

DEFINITION:

Remote; farther from any point of reference; opposed to proximal.

cyclic AMP

DEFINITION:

Cyclic adenosine monophosphate.

generation

DEFINITION:

1. The act or process of reproduction.

2. A class composed of all individuals removed by the same number of successive ancestors from a common predecessor, or occupying positions on the same level in a genealogic chart.

vasopressin receptor

DEFINITION:

A molecular structure to which the hormone, vasopressin, binds. See also receptor .

binding

DEFINITION:

1. Wrapping with a binder or bandage.

2. Forming a weak, reversible chemical bond, e.g., antigen to antibody or hormone to receptor.

osmotic water permeability

DEFINITION:

The ability to channel water across a membrane in response to a concentration gradient.

permission

DEFINITION:

Formal consent; authorization.