nephrogenic diabetes insipidus

DEFINITION:

A syndrome of polyuria and hyposthenuria caused by the failure of the renal tubules to reabsorb water in response to antidiuretic hormone, without disturbance in the renal filtration and solute excretion rates; the condition does not respond to exogenous vasopressin. It may be inherited as a rare X-linked trait or be acquired as a result of drug therapy or systemic disease.

adverse

DEFINITION:

1. Acting against or in a contrary direction.

2. Opposed to one's interests; unfavorable.

diabetes insipidus

DEFINITION:

A disorder of the pituitary gland characterized by intense thirst and by the excretion of large amounts of urine.

diabetes insipidus, central - A metabolic disorder due to injury of the neurohypophyseal system, which results in a deficient quantity of antidiuretic hormone being released or produced, and thus in failure of tubular reabsorption of water in the kidney. As a result, a large amount of urine of low specific gravity is excreted, followed by dehydration and great thirst; it is often attended by voracious appetite, loss of strength, and emaciation. It may be inherited, acquired, or idiopathic.

diabetes insipidus, nephrogenic - A syndrome of polyuria and hyposthenuria caused by the failure of the renal tubules to reabsorb water in response to antidiuretic hormone, without disturbance in the renal filtration and solute excretion rates; the condition does not respond to exogenous vasopressin. It may be inherited as a rare X-linked trait or be acquired as a result of drug therapy or systemic disease.

diabetes insipidus, pituitary - Central diabetes insipidus (See above).

potassium

DEFINITION:

A metallic element of the alkali group, many of whose salts are used in medicine. Potassium is the chief positively-charged ion of muscle and most other cells (intracellular fluid).

potassium

DEFINITION:

A metallic element of the alkali group, many of whose salts are used in medicine. Potassium is the chief positively-charged ion of muscle and most other cells (intracellular fluid).