interior
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- interior
Used in 63 Article translations
Used in 63 Article translations
- A Role for K268 in V2R Folding
- Altered Expression of COX-1, COX-2, and mPGES in Rats with Nephrogenic and Central Diabetes Insipidus
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- Amphotericin B Decreases Adenylyl Cyclase Activity and Aquaporin-2 Expression in Rat Kidney
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Apical Membrane Vesicles of ADH-stimulated Toad Bladder are Highly Water Permeable
- Appropriate Polarization Following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-Linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Correlation between Magnetic Resonance Imaging of Posterior Pituitary and Neurohypophyseal Function in Children with Diabetes Insipidus
- Cytoplasmic Dilution Induces Antidiuretic Hormone Water Channel Retrieval in Toad Urinary Bladder
- Desmopressin for Nocturnal Enuresis in Nephrogenic Diabetes Insipidus
- Effect of an Acute Oral Ibuprofen Intake on Urinary Aquaporin-2 Excretion in Healthy Humans
- Functional Involvement of VAMP/Synaptobrevin-2 in cAMP-Stimulated Aquaporin 2 Translocation in Renal Collecting Duct Cells
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Insulin Potentiates AVP-induced AQP2 Expression in Cultured Renal Collecting Duct Principal Cells
- Kinetics of Urea and Water Permeability Activation by Vasopressin in Rat Terminal IMCD
- Long-Term Regulation of Urinary Concentrating Capacity
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Mechanisms and Regulation of Water Transport in the Kidney
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus Caused By Mutation of Tyr205: A Key Residue of V2 Vasopressin Receptor Function
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Pathogenesis and Treatment of Autosomal-Dominant Nephrogenic Diabetes Insipidus Caused by an Aquaporin 2 Mutation
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Relief of Nocturnal Enuresis by Desmopressin is Kidney and Vasopressin Type 2 Receptor Independent
- Renal Aquaporins
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Rho Inhibits cAMP-Induced Translocation of Aquaporin-2 into the Apical Membrane of Renal Cells
- Severely Impaired Urine-Concentrating Ability in Mice Lacking the CLC-K1 Chloride Channel
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Hydrophobic Amino Acid Residues in the Membrane-Proximal C Tail of the G Protein-Coupled Vasopressin V2 Receptor are Necessary for Transport-Competent Receptor Folding
- The Ins and Outs of Aquaporin-2 Trafficking
- The Role of Membrane Turnover in the Water Permeability Response to Antidiuretic Hormone
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Therapeutic Potential of Vasopressin Receptor Antagonists
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Two Novel Aquaporin-2 Mutations Responsible for Congenital Nephrogenic Diabetes Insipidus in Chinese Families
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
Used in 25 Proceeding translations
Used in 25 Proceeding translations
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Clinical Phenotype and Molecular Characterization of A Mutant V2 Receptor Associated with Partial Congenital Nephrogenic Diabetes Insipidus
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Compartmentalization of NDI-causing vasopressin V2 receptor mutants in the early secretory pathway
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- Gene Mutation Analysis of NDI patients in Japan
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- N-linked glycosylation is essential for transport of the Aquaporin-2 water channel to the plasma membrane in MDCK cells
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Quality control of nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutants in the ER and in the ER/Golgi intermediate compartment
- Regulation of AQP2 trafficking and recycling by dopamine, PGE2 and ANP: involvement of AQP2-S256 phosphorylation
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- The C-terminus as a determinant for vasopressin receptors sorting
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane



