intracellular
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- intracellular
Used in 61 Article abstracts
Used in 61 Article abstracts
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- CHIP28 Water Channels are Localized in Constitutively Water-Permeable Segments of the Nephron
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Cellular Mechanisms of Aquaporin Trafficking
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Downregulation of Aquaporin-2 and -3 in Aging Kidney is Independent of V2 Vasopressin Receptor
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Endocytosis in Renal Proximal Tubules. Experimental Electron Microscopical Studies of Protein Absorption and Membrane Traffic in Isolated, In Vitro Perfused Proximal Tubules
- Extracellular Nucleotide Receptor Inhibits AVP-Stimulated Water Permeability in Inner Medullary Collecting Duct
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Water Channels Are Present in Clathrin-coated Vesicles from Bovine Kidney but Not from Brain
- GIP, a G-Protein-Coupled Receptor Interacting Protein
- Glycosylation is Important for Cell Surface Expression of the Water Channel Aquaporin-2, But is Not Essential for Tetramerization in the Endoplasmic Reticulum
- Heterodimerization of V1a and V2 Vasopressin Receptors Determines the Interaction with Beta-Arrestin and their Trafficking Patterns
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of Mutations in the Arginine Vasopressin Receptor 2 Gene Causing Nephrogenic Diabetes Insipidus in Chinese Patients
- Inheritance of Mutations in the V2 Receptor Gene in Thirteen Families with Nephrogenic Diabetes Insipidus
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Investigation of Folding and Degradation of In Vitro Synthesized Mutant Proteins in Microsomes
- Lithium-induced Nephrogenic Diabetes Insipidus
- Loss of Calcineurin Aα Results in Altered Trafficking of AQP2 and in Nephrogenic Diabetes Insipidus
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Pathogenesis of Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus: Functional Analysis of New AVPR2 Mutations Identified in Italian Families
- Nephrogenic diabetes insipidus.
- Pharmacological Chaperones: A New Twist on Receptor Folding
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Physiology and Pathophysiology of Renal Aquaporins
- Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Reconstitution of a Regulated Transepithelial Water Pathway in Cells Transfected with AQP2 and an AQP1/AQP2 Hybrid Containing the AQP2-C Terminus
- Redistribution of Aquaporin-2 Water Channels Induced by Vasopressin in Rat Kidney Inner Medullary Collecting Duct
- Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct
- Routing of the aquaporin-2 water channel in health and disease.
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-Induced Antidiuresis Through Activation of Rho
- The Proteasome is Involved in the Degradation of Different Aquaporin-2 Mutants Causing Nephrogenic Diabetes Insipidus
- The role of actin remodeling in the trafficking of intracellular vesicles, transporters, and channels: focusing on aquaporin-2
- Three Families with Autosomal Dominant Nephrogenic Diabetes Insipidus Caused by Aquaporin-2 Mutations in the C-terminus
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin Receptor Mutations Causing Nephrogenic Diabetes Insipidus
- Vasopressin and Oxytocin Receptors Coupled to Ca2+ Mobilization in Rat Inner Medullary Collecting Duct
- [Diseases Caused by Disorders of Membrane Transport: an Overview] (Japanese)
- [Recent Advances in Vasopressin Receptors and Signal Transduction System] (Japanese)
Used in 6 Article bodies
Used in 6 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus in a Patient Taking Cidofovir
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
Used in 23 Article translations
Used in 23 Article translations
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Mutations and Diseases of G Protein Coupled Receptors
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Rescue of a Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutant by Cell-Penetrating Peptides
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Aquaporin Family of Water Channels in Kidney: an Update on Physiology and Pathophysiology of Aquaporin-2
- The Proteasome is Involved in the Degradation of Different Aquaporin-2 Mutants Causing Nephrogenic Diabetes Insipidus
- Two Novel Mutations in the Aquaporin-2 and the Vasopressin V2 Receptor Genes in Patients with Congenital Nephrogenic Diabetes Insipidus
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Unrelated Japanese Kindreds with Nephrogenic Diabetes Insipidus
- Vasopressin and Oxytocin Receptors
- Water Channels
- Water Channels and Urea Transporters
Used in 28 Proceeding abstracts
Used in 28 Proceeding abstracts
- Analysis of molecular mechanisms causing V2 vasopressin receptor dysfunction in four patients with X-linked nephrogenic diabetes insipidus
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Clinical Phenotype and Molecular Characterization of A Mutant V2 Receptor Associated with Partial Congenital Nephrogenic Diabetes Insipidus
- Congenital (present a birth) severe diabetes insipidus. Most patients have nephrogenic diabetes insipidus (NDI), but some patients have autosomal recessive central (neurogenic) diabetes insipidus
- Decrease in urine volume and increase in urine osmolality after SR49059 administration in five adult male patients with X-linked nephrogenic diabetes insipidus
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- GIP, a G protein coupled receptor interacting protein
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Mutations of the vasopressin V2 receptor gene in X-linked Nephrogenic Diabetes Insipidus: functional analysis of receptor mutants and identification of new mutations in Italian families.
- Nephrogenic diabetes insipidus in Italian families
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Structural evolution of the V2 vasopressin receptor in mammals
- Structure-Function Analysis of the V2 Vasopressin Receptor
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- The C-terminus as a determinant for vasopressin receptors sorting
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- V2 Vasopressin Receptors in NDI: Where did they go?
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- V2 vasopressin receptor-arrestin interactions
- Variations in clinical phenotype associated with different mutations of the V2 receptor gene in X-linked recessive congenital nephrogenic DI (xCNDI)
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane
Used in 14 Proceeding translations
Used in 14 Proceeding translations
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Identification of proteins involved in the vasopressin-induced shuttle of aquaporin-2
- Modulation of vasopressin-dependent AQP2 expression in cultured mpkCCDc14 collecting duct principal cells by aldosterone, insulin, and hypertonicity
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Nephrogenic diabetes insipidus in Italian families
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Structure-Function Analysis of the V2 Vasopressin Receptor
- The C-terminus as a determinant for vasopressin receptors sorting
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane
Used in 34 Term definitions
Used in 34 Term definitions
- C-terminus
- G protein
- G proteins
- G-protein
- GTP binding proteins
- GTP-binding protein
- GTP-binding proteins
- Microspora
- Mycobacterium leprae
- Toxoplasma gondii
- adenylyl cyclase
- cAMP-dependent protein kinase
- carboxy-terminus
- cyclic adenosine monophosphate
- cyclic guanosine monophosphate
- endosome
- endosomes
- forskolin
- hypertonic dehydration
- hypokalemic alkalosis
- infection
- insulin
- lysosomal storage disease
- lysosome
- lysosomes
- malaria
- matrix
- neurofilament
- orthophosphate
- polarity
- potassium
- protein kinase C
- signal transduction
- vasopressin-regulated water channels
