kidney collecting duct cells
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- kidney collecting duct cells
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Kidney collecting duct cells are cells which are mainly located in the medulla of the kidney. In the kidney, the blood fluid is filtered into tubules (nephrons) where electrolytes, water, and many other components are reabsorbed or even secreted. Collecting duct cells are at the end of such nephrons. Here, water is reabsorbed from the urine, and therefore, urine becomes concentrated. Reabsorption of water in collecting duct cells is regulated by the V2 vasopressin receptor. Inactivating mutations of V2 vasopressin receptor result in a loss of water reabsorption in collecting duct cells—the cause of nephrogenic diabetes insipidus (Schöneberg).
Used in 5 Article abstracts
Used in 5 Article abstracts