passive cutaneous anaphylaxis
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- passive cutaneous anaphylaxis
-
A passively transferred local anaphylactic reaction used in the study of reaginic antibodies; the skin of an animal is sensitized by intradermal injection of serum from a sensitized animal, and after a 24- to 72-hour latent period the antigen and Evans blue dye are injected intravenously. Reaction of the antigen with skin-fixed antibody causes the release of histamine, which increases vascular permeability, permits leakage of the albumin -bound dye, and produces a blue spot at the site of the intradermal injection. Abbreviated PCA.
Used in 2 Term definitions
Used in 2 Term definitions