plasma membrane
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- plasma membrane
Used in 72 Article abstracts
Used in 72 Article abstracts
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- An Aquaporin-2 Water Channel Mutant Which Causes Autosomal Dominant Nephrogenic Diabetes Insipidus is Retained in the Golgi Complex
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Apparent Loss-of-Function Mutant GPCRs Revealed as Constitutively Desensitized Receptors
- Appropriate Polarization Following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-Linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
- Aquaporin-2, a Vasopressin-sensitive Water Channel, and Nephrogenic Diabetes Insipidus
- Association of Calnexin With Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Cell-Biologic and Functional Analyses of Five New Aquaporin-2 Missense Mutations that Cause Recessive Nephrogenic Diabetes Insipidus
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Cellular and Subcellular Localization of the Vasopressin-Regulated Urea Transporter in Rat Kidney
- Characterization of an Aquaporin-2 Water Channel Gene Mutation Causing Partial Nephrogenic Diabetes Insipidus in a Mexican Family: Evidence of Increased Frequency of the Mutation in the Town of Origin
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Congenital Nephrogenic Diabetes Insipidus
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Constitutive Arrestin-Mediated Desensitization of a Human Vasopressin Receptor Mutant Associated with Nephrogenic Diabetes Insipidus
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Cyclic AMP is Sufficient for Triggering the Exocytic Recruitment of Aquaporin-2 in Renal Epithelial Cells
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Diffusion in the Endoplasmic Reticulum of an Aquaporin-2 Mutant Causing Human Nephrogenic Diabetes Insipidus
- Disordered Water Channel Expression and Distribution in Acquired Nephrogenic Diabetes Insipidus
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Expression of VAMP-2-Like Protein in Kidney Collecting Duct Intracellular Vesicles. Colocalization with Aquaporin-2 Water Channels
- Functional Analysis of Aquaporin-2 Mutants Associated with Nephrogenic Diabetes Insipidus by Yeast Expression
- Functional Involvement of VAMP/Synaptobrevin-2 in cAMP-Stimulated Aquaporin 2 Translocation in Renal Collecting Duct Cells
- Functional Water Channels Are Present in Clathrin-coated Vesicles from Bovine Kidney but Not from Brain
- Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.
- GIP, a G-Protein-Coupled Receptor Interacting Protein
- Glycosylation is Important for Cell Surface Expression of the Water Channel Aquaporin-2, But is Not Essential for Tetramerization in the Endoplasmic Reticulum
- Heterodimerization of V1a and V2 Vasopressin Receptors Determines the Interaction with Beta-Arrestin and their Trafficking Patterns
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Membrane Traffic After Inhibition of Endocytosis in Renal Proximal Tubules
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic diabetes insipidus.
- Novel Mutations in Aquaporin-2 Gene in Female Siblings with Nephrogenic Diabetes Insipidus: Evidence of Disrupted Water Channel Function
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor
- Redistribution of Aquaporin-2 Water Channels Induced by Vasopressin in Rat Kidney Inner Medullary Collecting Duct
- Regional Time-Dependent Changes in Vasopressin V2 Receptor Expression in the Rat Kidney During Water Restriction
- Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct
- Relationship Between Vasopressin-Sensitive Water Transport and Plasma Membrane Fluidity in Kidney Collecting Tubule
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Role of Renal Aquaporins in Escape from Vasopressin-induced Antidiuresis in Rat
- Ser-256 Phosphorylation Dynamics of Aquaporin 2 During Maturation From the Endoplasmic Reticulum to the Vesicular Compartment in Renal Cells
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-Induced Antidiuresis Through Activation of Rho
- The role of actin remodeling in the trafficking of intracellular vesicles, transporters, and channels: focusing on aquaporin-2
- Two Novel Aquaporin-2 Mutations Responsible for Congenital Nephrogenic Diabetes Insipidus in Chinese Families
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin Receptor Mutations Causing Nephrogenic Diabetes Insipidus
- Vasopressin Receptor Mutations and Nephrogenic Diabetes Insipidus
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
Used in 6 Article translations
Used in 6 Article translations
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Water Channels
Used in 38 Proceeding abstracts
Used in 38 Proceeding abstracts
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- An impaired routing of wild type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Biochemical Characterization of Partial Nephrogenic Diabetes Insipidus (NDI) Phenotypes
- Cell biological and functional analysis of five new Aquaporin-2 gene missense mutations in recessive Nephrogenic Diabetes Insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Chemical Chaperones as a Novel Therapeutic Strategy for NDI
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Compartmentalization of NDI-causing vasopressin V2 receptor mutants in the early secretory pathway
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Decreased Aquaporin-2 Water Channel Expression in Acquired Nephrogenic Diabetes Insipidus
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- GIP, a G protein coupled receptor interacting protein
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Identification of proteins involved in the vasopressin-induced shuttle of aquaporin-2
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- N-linked glycosylation is essential for transport of the Aquaporin-2 water channel to the plasma membrane in MDCK cells
- Nephrogenic Diabetes Insipidus Patients in Japan
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Quality control of nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutants in the ER and in the ER/Golgi intermediate compartment
- Regulation of AQP2 trafficking and recycling by dopamine, PGE2 and ANP: involvement of AQP2-S256 phosphorylation
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane
Used in 29 Term definitions
Used in 29 Term definitions
- CTL
- G protein
- G proteins
- G-protein
- NADPH oxidase
- Na+,K+-ATPase
- Paramyxoviridae
- Retroviridae
- apical plasma membrane
- basolateral membranes
- basolateral plasma membrane
- blank
- cell
- cell membrane
- cell plasma membranes
- cell surface
- cell wall
- cytotoxic T lymphocytes
- endocytosis
- macrophage
- mammalian type B retroviruses
- mammalian type C retroviruses
- membrane
- membrane transport protein
- myelin sheath
- phagocytosis
- sarcolemma
- signal transduction
- water channel



