rat
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- rat
-
Any of numerous small rodents of the genus Rattus and related genera of the family Muridae; many are aggressive and omnivorous pests found about human habitations. Rats not only cause great economic loss but are vectors of human disease; they harbor at least eleven species of intestinal parasites that are transmissible to humans, such as tapeworms, roundworms, and trichinae, and they are reservoirs for the infective agents of plague, typhus, Weil's disease, and rat-bite fever. Albino mutants of Rattus norvegicus are used as laboratory animals.
Used in 81 Article abstracts
Used in 81 Article abstracts
- 125I-d(CH2)5[Tyr(Me)2, Tyr(NH2)9]AVP: Iodination and Binding Characteristics of a Vasopressin Receptor Ligand
- A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells
- A New Series of Photoactivatable and Iodinatable Linear Vasopressin Antagonists
- Acute Effects of Vasopressin V2-Receptor Antagonist on Kidney AQP2 Expression and Subcellular Distribution
- Altered Expression of Major Renal Na Transporters in Rats with Unilateral Ureteral Obstruction
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Co-transporter, and Epithelial Sodium Channel
- Apical Extracellular Calcium/Polyvalent Cation-sensing Receptor Regulates Vasopressin-elicited Water Permeability in Rat Kidney Inner Medullary Collecting Duct
- Application of Difference Gel Electrophoresis (DIGE) to the Identification of Inner Medullary Collecting Duct Proteins
- Aquaporin-2 Expression in Primary Cultured Rat Inner Medullary Collecting Duct Cells
- Aquaporins in Complex Tissues: Distribution of Aquaporins 1-5 in Human and Rat Eye
- Atrial Natriuretic Factor Inhibits Vasopressin-Stimulated Osmotic Water Permeability in Rat Inner Medullary Collecting Duct
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- CHIP28 Water Channels are Localized in Constitutively Water-Permeable Segments of the Nephron
- Calcium and Cyclic Adenosine Monophosphate as Second Messengers for Vasopressin in the Rat Inner Medullary Collecting Duct
- Cellular Mechanism of Lithium-Induced Nephrogenic Diabetes Insipidus in Rats
- Cellular and Subcellular Localization of the Vasopressin-Regulated Urea Transporter in Rat Kidney
- Changes of Rat Kidney AQP2 and Na,K-ATPase mRNA Expression in Lithium-Induced Nephrogenic Diabetes Insipidus
- Characterization of Purified Endosomes Containing the Antidiuretic Hormone-Sensitive Water Channel From Rat Renal Papilla
- Characterization of SR 121463A, A Highly Potent and Selective, Orally Active Vasopressin V2 Receptor Antagonist
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Cloning, Characterization, and Chromosomal Mapping of Human Aquaporin of Collecting Duct
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Do Aquaporins Have a Role in Nocturnal Enuresis?
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- Evidence for Dual Signaling Pathways for V2 Vasopressin Receptor in Rat Inner Medullary Collecting Duct
- Experimental Tests of Three-Dimensional Model of Urinary Concentrating Mechanism
- Extracellular Nucleotide Receptor Inhibits AVP-Stimulated Water Permeability in Inner Medullary Collecting Duct
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Hormone and Autacoid Regulation of cAMP Production in Rat IMCD Subsegments
- Hypokalemia-Induced Downregulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla and Cortex
- Identification of Agonist Binding Sites of Vasopressin and Oxytocin Receptors
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Influence of Acute Elevation of Plasma AVP Level on Rat Vasopressin V2 Receptor and Aquaporin-2 mRNA Expression
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Long-Term Regulation of Four Renal Aquaporins in Rats
- Mechanism of Lithium-Induced Polyuria in the Rat
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Membrane Traffic After Inhibition of Endocytosis in Renal Proximal Tubules
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Mechanisms of Urea Transport
- Mutations in the Vasopressin Type 2 Receptor Gene (AVPR2) Associated with Nephrogenic Diabetes Insipidus
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Nonmuscle Myosin II and Myosin Light Chain Kinase are Downstream Targets for Vasopressin Signaling in the Renal Collecting Duct
- Novel Down-Regulatory Mechanism of the Surface Expression of Vasopressin V2 Receptor by an Alternative Splice Receptor Variant
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Oxytocin as an Antidiuretic Hormone. II. Role of V2 Vasopressin Receptor
- Pathophysiology of Renal Fluid Retention
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Redistribution of Aquaporin-2 Water Channels Induced by Vasopressin in Rat Kidney Inner Medullary Collecting Duct
- Regional Time-Dependent Changes in Vasopressin V2 Receptor Expression in the Rat Kidney During Water Restriction
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Reverse Pharmacological Effect of Loop Diuretics and Altered rBSC1 Expression in Rats with Lithium Nephropathy
- Syntaxin-4 is Localized to the Apical Plasma Membrane of Rat Renal Collecting Duct Cells: Possible Role in Aquaporin-2 Trafficking
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-Induced Antidiuresis Through Activation of Rho
- Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Treating lithium-induced nephrogenic diabetes insipidus with a COX-2 inhibitor improves polyuria via upregulation of AQP2 and NKCC2.
- Vasopressin Activates Collecting Duct Urea Transporters and Water Channels by Distinct Physical Processes
- Vasopressin Effects on Urea and H20 Transport in Inner Medullary Collecting Duct Subsegments
- Vasopressin Increases Water Permeability of Kidney Collecting Duct by Inducing Translocation of Aquaporin-CD Water Channels to Plasma Membrane
- Vasopressin and Oxytocin Receptors Coupled to Ca2+ Mobilization in Rat Inner Medullary Collecting Duct
- Vasopressin- and cAMP-Induced Changes in Ultrastructure of Isolated Perfused Inner Medullary Collecting Ducts
- Vasopressin-Independent Regulation of Collecting Duct Water Permeability
- Water Channel Aquaporin-2 Directly Binds to Actin
- Water Channels and Urea Transporters
- Water Permeability and Fluidity of Renal Basolateral Membranes
- Xanthopterin-Induced Renal Dysfunction: A Reversible Model of Crystal Nephropathy
- [Recent Advances in Vasopressin Receptors and Signal Transduction System] (Japanese)
Used in 9 Article bodies
Used in 9 Article bodies
- A Congenital Renal Tubular Defect
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hyperosmolar Coma and Lithium-induced Diabetes Insipidus
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Indomethacin
- Persistent Nephrogenic Diabetes Insipidus Following Lithium Therapy
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients
Used in 32 Article translations
Used in 32 Article translations
- A Compartmental Model Predicts that Dietary Potassium Affects Lithium Dynamics in Rats
- ADH Resistance of LLC-pk1 Cells Caused by Overexpression of cAMP-Phosphodiesterase Type-IV
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Co-transporter, and Epithelial Sodium Channel
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Cloning, Characterization, and Chromosomal Mapping of Human Aquaporin of Collecting Duct
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Isolation of Human aquaporin-CD Gene
- Kinetic Model of Water and Urea Permeability Regulation by Vasopressin in Collecting Duct
- Kinetics of Urea and Water Permeability Activation by Vasopressin in Rat Terminal IMCD
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Recent Advances in Water Transport
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Renal Aquaporins
- Role of Sodium Depletion in Acute Antidiuretic Effect of Bendroflumethiazide in Rats with Nephrogenic Diabetes Insipidus
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Vasopressin Effects on Urea and H20 Transport in Inner Medullary Collecting Duct Subsegments
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
Used in 16 Proceeding abstracts
Used in 16 Proceeding abstracts
- An impaired routing of wild type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Cotransporter and Epithelial Sodium Channel
- Aquaporin 2-containing Apical Membrane Endosomes (AQP-2 Endosomes) Possess a Multiprotein Signaling Complex
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Dysregulation of genes in rats with lithium-induced NDI
- Functional investigations of the vasopressin regulated antidiuretic machinery in single inner medullary collecting duct (IMCD) cells
- Identification of proteins involved in the vasopressin-induced shuttle of aquaporin-2
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- Osmolality and solute composition regulate aquaporin-2 expression in primary cultured renal principal cells
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Regulation of AQP2 trafficking and recycling by dopamine, PGE2 and ANP: involvement of AQP2-S256 phosphorylation
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
Used in 6 Proceeding translations
Used in 6 Proceeding translations
- Regulation of UT-A1 abundance by vasopressin and glucocorticoids
- Candesartan treatment prevents dysregulation of AQP2, BSC-1 and NaPi2 in ureteral obstruction-induced NDI
- Functional investigations of the vasopressin regulated antidiuretic machinery in single inner medullary collecting duct (IMCD) cells
- Modulation of aquaporin-2 expression in primary cultured rat inner medullary collecting duct (IMCD) cells
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Vasopressin-Independent Regulation of Aquaporin-2 Protein



