regulated
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- regulated
-
1. Having been adjusted to a certain standard.
2. In biology, describing the adaptation of form or behavior of an organism to changed conditions.
Used in 79 Article abstracts
Used in 79 Article abstracts
- Acute Effects of Vasopressin V2-Receptor Antagonist on Kidney AQP2 Expression and Subcellular Distribution
- Amphotericin B Decreases Adenylyl Cyclase Activity and Aquaporin-2 Expression in Rat Kidney
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Aquaporin-2 Expression in Primary Cultured Rat Inner Medullary Collecting Duct Cells
- Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
- Aquaporin-2: COOH Terminus is Necessary But Not Sufficient for Routing to the Apical Membrane
- Aquaporins in the Kidney: From Molecules to Medicine
- Aquaporins: Roles in Renal Function and Peritoneal Dialysis
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- CHIP28 Water Channels are Localized in Constitutively Water-Permeable Segments of the Nephron
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Cellular and Subcellular Localization of the Vasopressin-Regulated Urea Transporter in Rat Kidney
- Changes of Rat Kidney AQP2 and Na,K-ATPase mRNA Expression in Lithium-Induced Nephrogenic Diabetes Insipidus
- Cloning and Expression of Apical Membrane Water Channel of Rat Kidney Collecting Tubule
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Constitutive Nitric Oxide Synthase in Hypothalami of Normal and Hereditary Diabetes Insipidus Rats and Mice: Role of Nitric Oxide in Osmotic Regulation and its Mechanism
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Decreased Vasopressin-Mediated Renal Water Reabsorption in Rats with Compensated Liver Cirrhosis
- Diabetes Insipidus (Hendy, Bichet)
- Diabetes Insipidus in Children: Pathophysiology, Diagnosis and Management
- Disordered Water Channel Expression and Distribution in Acquired Nephrogenic Diabetes Insipidus
- Do Aquaporins Have a Role in Nocturnal Enuresis?
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- Escape from Vasopressin-Induced Antidiuresis: Role of Vasopressin Resistance of the Collecting Duct
- Expression of VAMP-2-Like Protein in Kidney Collecting Duct Intracellular Vesicles. Colocalization with Aquaporin-2 Water Channels
- Expression of Vasopressin V1a and V2 Receptor Messenger Ribonucleic Acid in the Liver and Kidney of Embryonic, Developing, and Adult Rats
- Glycosylation is Important for Cell Surface Expression of the Water Channel Aquaporin-2, But is Not Essential for Tetramerization in the Endoplasmic Reticulum
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Kinetics of Urea and Water Permeability Activation by Vasopressin in Rat Terminal IMCD
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Long-Term Regulation of Urinary Concentrating Capacity
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pathophysiology of Renal Fluid Retention
- Physiology and Pathophysiology of Renal Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Proteomic Analysis of Long-Term Vasopressin Action in Inner Medullary Collecting Duct of Brattleboro Rat
- Quantitation of Aquaporin-2 Abundance in Microdissected Collecting Ducts: Axial Distribution and Control by AVP
- Rat Renal Arcade Segment Expresses Vasopressin-regulated Water Channel and Vasopressin V2 Receptor
- Reconstitution of a Regulated Transepithelial Water Pathway in Cells Transfected with AQP2 and an AQP1/AQP2 Hybrid Containing the AQP2-C Terminus
- Redistribution of Aquaporin-2 Water Channels Induced by Vasopressin in Rat Kidney Inner Medullary Collecting Duct
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Regulation of V2 Vasopressin Receptor Degradation by Agonist Promoted Ubiquitination
- Renal Aquaporins
- Renal Aquaporins: Key Roles in Water Balance and Water Balance Disorders
- Renal Water Channel Expression in Newborns: Measurement of Urinary Excretion of Aquaporin-2
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of Aquaporins in Water Balance Disorders
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Ser-256 Phosphorylation Dynamics of Aquaporin 2 During Maturation From the Endoplasmic Reticulum to the Vesicular Compartment in Renal Cells
- Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- Syntaxin-4 is Localized to the Apical Plasma Membrane of Rat Renal Collecting Duct Cells: Possible Role in Aquaporin-2 Trafficking
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Ins and Outs of Aquaporin-2 Trafficking
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The role of actin remodeling in the trafficking of intracellular vesicles, transporters, and channels: focusing on aquaporin-2
- Three Families with Autosomal Dominant Nephrogenic Diabetes Insipidus Caused by Aquaporin-2 Mutations in the C-terminus
- Two Novel Aquaporin-2 Mutations Responsible for Congenital Nephrogenic Diabetes Insipidus in Chinese Families
- Urinary Excretion of Aquaporin-2 in Patients with Diabetes Insipidus
- Urinary Excretion of Aquaporin-2 in Term and Preterm Infants
- Vasopressin Increases Water Permeability of Kidney Collecting Duct by Inducing Translocation of Aquaporin-CD Water Channels to Plasma Membrane
- Vasopressin Receptors in Health and Disease
- Vasopressin-elicited Water and Urea Permeabilities are Altered in IMCD in Hypercalcemic Rats
- [Recent Advances in Vasopressin Receptors and Signal Transduction System] (Japanese)
- cDNA Array Identification of Genes Regulated in Rat Renal Medulla in Response to Vasopressin Infusion
- cDNA Cloning of a Functional Water Channel From Toad Urinary Bladder Epithelium
Used in 51 Article translations
Used in 51 Article translations
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Aquaporin-2 Water Channel Mutations and Nephrogenic Diabetes Insipidus: New Variations on a Theme
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Assignment of the Human Gene for the Water Channel of Renal Collecting Duct Aquaporin 2 (AQP2) to Chromosome 12 Region q12-->q13
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Constitutive Nitric Oxide Synthase in Hypothalami of Normal and Hereditary Diabetes Insipidus Rats and Mice: Role of Nitric Oxide in Osmotic Regulation and its Mechanism
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Cytoplasmic Dilution Induces Antidiuretic Hormone Water Channel Retrieval in Toad Urinary Bladder
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- From Vasopressin Receptor to Water Channel: Intracellular Traffic, Constraint and By-pass
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Hyponatremia and Hypernatremia
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Isolation of Human aquaporin-CD Gene
- Kinetics of Urea and Water Permeability Activation by Vasopressin in Rat Terminal IMCD
- Long-Term Regulation of Urinary Concentrating Capacity
- Mechanism of Vasopressin Action in the Renal Collecting Duct
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Mechanisms and Regulation of Water Transport in the Kidney
- Molecular Mechanisms for the Regulation of Water Transport in Amphibian Epithelia by Antidiuretic Hormone
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pathophysiology of the Aquaporin Water Channels
- Physiology and Pathophysiology of Aquaporins
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Recent Advances in Water Transport
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Regulation of V2 Vasopressin Receptor Degradation by Agonist Promoted Ubiquitination
- Renal Aquaporins
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Role of Aquaporin Water Channels in Kidney and Lung
- Severe Lactic Acidosis and Renal Involvement in a Patient with Relapsed Burkitt's Lymphoma
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- The Aquaporin Family of Molecular Water Channels
- The Aquaporin Family of Water Channels in Kidney: an Update on Physiology and Pathophysiology of Aquaporin-2
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- Transient Central Diabetes Insipidus in the Setting of Underlying Chronic Nephrogenic Diabetes Insipidus Associated with Lithium Use
- Vasopressin Receptors in Health and Disease
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin-elicited Water and Urea Permeabilities are Altered in IMCD in Hypercalcemic Rats
- Water Channels
- cDNA Cloning of a Functional Water Channel From Toad Urinary Bladder Epithelium
Used in 28 Proceeding abstracts
Used in 28 Proceeding abstracts
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Correction of age-related polyuria by dDAVP: Molecular involvement of aquaporins and urea transporters
- Decreased Aquaporin-2 Water Channel Expression in Acquired Nephrogenic Diabetes Insipidus
- Defective urinary concentrating function in transgenic mice lacking urea transporter UT-B
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Mono-ubiquitination and missorting to lysosomes of the Aquaporin-2 water channel mutant AQP2-E258K explains dominant Nephrogenic Diabetes Insipidus
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- Progress in the function and structure of aquaporin-1 and aquaporin-2
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Regulation of AQP2 trafficking and recycling by dopamine, PGE2 and ANP: involvement of AQP2-S256 phosphorylation
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
- Urinary Aquaporin-2 in Diagnosis of Disorders of Water Metabolism
- V2 vasopressin receptor-deficient mouse model: Pathophysiological changes and therapeutical implications
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 7 Proceeding translations
Used in 7 Proceeding translations
- Expressional alteration of sodium transporter in the thick ascending limb of Henle and urinary concentration
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Urinary Aquaporin-2 in Diagnosis of Disorders of Water Metabolism
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct



