specific
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- specific
-
1. Pertaining to a species.
2. Produced by a single kind of microorganism.
3. Restricted in application, effect, etc., to a particular structure, function, etc.
4. A remedy specially indicated for any particular disease.
5. In immunology, pertaining to the special affinity of antigen for the corresponding antibody.
Used in 74 Article abstracts
Used in 74 Article abstracts
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Specific Antibody to Vasopressin in a Man with Concomitant Resistance to Treatment with Pitressin
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Apical Extracellular Calcium/Polyvalent Cation-sensing Receptor Regulates Vasopressin-elicited Water Permeability in Rat Kidney Inner Medullary Collecting Duct
- Aquaporins in Complex Tissues: Distribution of Aquaporins 1-5 in Human and Rat Eye
- CHIP28 Water Channels are Localized in Constitutively Water-Permeable Segments of the Nephron
- Clinical Use of Vasopressin Analogues
- Cloned Human Aquaporin-1 is a Cyclic GMP-gated Ion Channel
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Compound Deletion of the rhoGAP C1 and V2 Vasopressin Receptor Genes in a Patient with Nephrogenic Diabetes Insipidus
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
- Development of Urinary Concentrating Capacity: Role of Aquaporin-2
- Endocytosis in Renal Proximal Tubules. Experimental Electron Microscopical Studies of Protein Absorption and Membrane Traffic in Isolated, In Vitro Perfused Proximal Tubules
- Evaluation and Management of Diabetes Insipidus
- Evidence for Dual Signaling Pathways for V2 Vasopressin Receptor in Rat Inner Medullary Collecting Duct
- Expression of VAMP-2-Like Protein in Kidney Collecting Duct Intracellular Vesicles. Colocalization with Aquaporin-2 Water Channels
- Expression of Vasopressin V1a and V2 Receptor Messenger Ribonucleic Acid in the Liver and Kidney of Embryonic, Developing, and Adult Rats
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Genetic Restoration of Aldose Reductase to the Collecting Tubules Restores Maturation of the Urine Concentrating Mechanism
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Hereditary Vasopressin Resistance in Man and Mouse
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Human Platelet Fraction Arginine-Vasopressin. Potential Physiological Role
- Impaired Solute Accumulation in Inner Medulla of Clcnk1-/- Mice Kidney
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Induction of Intramembranous Particle Clusters in Mice with Nephrogenic Diabetes Insipidus
- Isolation of Human aquaporin-CD Gene
- Large-Scale Purification of Functional Recombinant Human Aquaporin-2
- Long Term Regulation of Aquaporin-2 Expression in Vasopressin-responsive Renal Collecting Duct Principal Cells
- Measurement of Osmolality in Kidney Slices Using Vapor Pressure Osmometry
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Molecular Basis of V2 Vasopressin Receptor/Gs Coupling Selectivity
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Mechanisms of Urea Transport
- Mutations in the V2 Vasopressin Receptor Gene are Associated with X-linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus: Close Linkage with Markers from the Distal Long Arm of the Human X Chromosome
- Novel Down-Regulatory Mechanism of the Surface Expression of Vasopressin V2 Receptor by an Alternative Splice Receptor Variant
- Novel Vasopressin Type 2 (AVPR2) Gene Mutations in Brazilian Nephrogenic Diabetes Insipidus Patients
- Overt Nephrogenic Diabetes Insipidus in Mice Lacking the CLC-K1 Chloride Channel
- Pathophysiology of the Aquaporin Water Channels
- Physiological Importance of Aquaporin Water Channels
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Polyuria and Polydipsia. Problems Associated with Patient Evaluation
- Rat Renal Arcade Segment Expresses Vasopressin-regulated Water Channel and Vasopressin V2 Receptor
- Recent Insights into the Coordinate Regulation of Body Water and Divalent Mineral Ion Metabolism
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Renal Haemodynamics, Sodium and Water Reabsorption During Continuous Intravenous Infusion of Recombinant Interleukin-2
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of cAMP-Phosphodiesterase Isozymes in Pathogenesis of Murine Nephrogenic Diabetes Insipidus
- Segment Specific ENaC Downregulation in Kidney of Rats with Lithium-Induced NDI
- Sequence-Specific "Gene Signatures" can be Obtained by PCR with Single Specific Primers at Low Stringency
- Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
- Switch from an Aquaporin to a Glycerol Channel by Two Amino Acids Substitution
- The Apical Compartment: Trafficking Pathways, Regulators and Scaffolding Proteins
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Transient Nephrogenic Diabetes Insipidus Accompanied by Possible Psychogenic Polydipsia
- Urinary Excretion of Aquaporin-2 in Patients with Diabetes Insipidus
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Vasopressin and Oxytocin Receptors
- Vasopressin-elicited Water and Urea Permeabilities are Altered in IMCD in Hypercalcemic Rats
- Water Channels and Urea Transporters
- Water Disturbances in Cardiac Failure
Used in 14 Article bodies
Used in 14 Article bodies
- A Congenital Renal Tubular Defect
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Index of Suspicion. Case 2. Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus Following High Dose Epirubicin Chemotherapy for Metastatic Soft Tissue Sarcoma [Letter]
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Nephrogenic Diabetes Insipidus--Prodromal Phase of Multiple Myeloma
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- Notes on Some Cases of Diabetes Insipidus with Marked Family and Hereditary Tendencies
- Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients
Used in 136 Article translations
Used in 136 Article translations
- 1-Desamino-8-D-Arginine Vasopressin (DDAVP) in Patients with Congenital Nephrogenic Diabetes Insipidus
- A Congenital Defect of Water Metabolism
- A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Mouse Model to Test the in vivo Efficacy of Chemical Chaperones
- A Role for K268 in V2R Folding
- Activation of the Vasopressin-sensitive Water Permeability Pathway in the Toad Bladder by N-ethyl Maleimide
- Amelioration of Polyuria in Nephrogenic Diabetes Insipidus Due to Aquaporin-2 Deficiency
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Co-transporter, and Epithelial Sodium Channel
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Assignment of the Human Gene for the Water Channel of Renal Collecting Duct Aquaporin 2 (AQP2) to Chromosome 12 Region q12-->q13
- Autosomal Recessive Nephrogenic Diabetes Insipidus Caused by an Aquaporin-2 Mutation
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Clinical Phenotype of Nephrogenic Diabetes Insipidus in Females Heterozygous for a Vasopressin Type 2 Receptor Mutation
- Clinical Utility of Direct Mutation Testing for Congenital Nephrogenic Diabetes Insipidus in Families
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Correlation between Magnetic Resonance Imaging of Posterior Pituitary and Neurohypophyseal Function in Children with Diabetes Insipidus
- Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Detection of Skewed X-Inactivation in Two Female Carriers of Vasopressin Type 2 Receptor Gene Mutation
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Differential Diagnosis and Pathophysiology of Diabetes Insipidus
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- Effect of an Acute Oral Ibuprofen Intake on Urinary Aquaporin-2 Excretion in Healthy Humans
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evidence for Intact V1-vasopressin Receptors in Congenital Nephrogenic Diabetes Insipidus
- Evidence for Stabilization of Aquaporin-2 Folding Mutants by N-linked Glycosylation in the Endoplasmic Reticulum
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Foscarnet Alters Antidiuretic Hormone-Mediated Transport
- From Vasopressin Receptor to Water Channel: Intracellular Traffic, Constraint and By-pass
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Functional Involvement of VAMP/Synaptobrevin-2 in cAMP-Stimulated Aquaporin 2 Translocation in Renal Collecting Duct Cells
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Rescue of the Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutants G185C and R202C by a Second Site Suppressor Mutation
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- GS-Activating Receptors: Modes of Transmembrane Signalling and Genetic Defects
- Genetic Restoration of Aldose Reductase to the Collecting Tubules Restores Maturation of the Urine Concentrating Mechanism
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Hyponatremia and Hypernatremia
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Index of Suspicion. Case 2. Nephrogenic Diabetes Insipidus
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Inheritance of Mutations in the V2 Receptor Gene in Thirteen Families with Nephrogenic Diabetes Insipidus
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Intracranial Calcification in Nephrogenic Diabetes Insipidus
- Isolation of Human aquaporin-CD Gene
- Linkage Analyses in Families with Nephrogenic Diabetes Insipidus
- Linkage of X-linked Nephrogenic Diabetes Insipidus with DXS52, a Polymorphic DNA Marker
- Lithium-Induced Diabetes Insipidus in a Surgical Patient: Report of a Case and Review of the Literature
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Mechanisms and Regulation of Water Transport in the Kidney
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Meniere's Disease in Congenital Nephrogenic Diabetes Insipidus: Report of Two Twins
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Aspects of Water Transport
- Molecular Biology of Diabetes Insipidus
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Insights into the Pathogenesis of Inherited Renal Tubular Disorders
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular and Cellular Biology of Vasopressin and Oxytocin Receptors and Action in the Kidney
- Mutations and Diseases of G Protein Coupled Receptors
- Mutations in the Founder of the MIP Gene Family Underlie Cataract Development in the Mouse
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2 Receptor and Aquaporin-2 Genes in 12 Families with Congenital Nephrogenic Diabetes Insipidus
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Nature and Recurrence of AVPR2 Mutations in X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus Caused By Mutation of Tyr205: A Key Residue of V2 Vasopressin Receptor Function
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Nephrogenic Diabetes Insipidus in Mice Lacking All Nitric Oxide Synthase Isoforms
- Nephrogenic Diabetes Insipidus in Sibling Colts
- Nephrogenic Diabetes Insipidus: Clinical Symptoms, Pathogenesis, Genetics and Treatment
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Normal Fibrinolytic Responses to 1-Desamino-8-D-Arginine Vasopressin in Patients with Nephrogenic Diabetes Insipidus Caused by Mutations in the Aquaporin 2 Gene
- Novel Mutations in the V2 Vasopressin Receptor Gene in Two Pedigrees with Congenital Nephrogenic Diabetes Insipidus
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Pathophysiology of the Aquaporin Water Channels
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Phosphorylation of the V2 Vasopressin Receptor
- Physiology and Pathophysiology of Aquaporins
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Polyuria in Childhood
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Reconstitution of a Regulated Transepithelial Water Pathway in Cells Transfected with AQP2 and an AQP1/AQP2 Hybrid Containing the AQP2-C Terminus
- Regulation of Membrane Permeability by Vasopressin; Activation of the Water Permeability Pathway in Toad Urinary Bladder by N-Ethyl-Maleimide
- Relationship Between Vasopressin-Sensitive Water Transport and Plasma Membrane Fluidity in Kidney Collecting Tubule
- Renal Histology in a Patient with Nephrogenic Diabetes Insipidus
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Role of Aquaporin Water Channels in Kidney and Lung
- Sequence-Specific "Gene Signatures" can be Obtained by PCR with Single Specific Primers at Low Stringency
- Severely Impaired Urine-Concentrating Ability in Mice Lacking the CLC-K1 Chloride Channel
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- Six Novel Mutations in the Vasopressin V2 Receptor Gene Causing Nephrogenic Diabetes Insipidus
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- Structure and Function of Kidney Water Channels
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Aquaporin Family of Water Channels in Kidney: an Update on Physiology and Pathophysiology of Aquaporin-2
- The Ins and Outs of Aquaporin-2 Trafficking
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Role of Membrane Turnover in the Water Permeability Response to Antidiuretic Hormone
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Transient Nephrogenic Diabetes Insipidus Accompanied by Possible Psychogenic Polydipsia
- Two Novel Mutations in the Aquaporin-2 and the Vasopressin V2 Receptor Genes in Patients with Congenital Nephrogenic Diabetes Insipidus
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Unrelated Japanese Kindreds with Nephrogenic Diabetes Insipidus
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Vasopressin Receptors in Health and Disease
- Vasopressin and Oxytocin Receptors
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Water Channels and Urea Transporters
- Water Transport Across Mammalian Cell Membranes
- cDNA Cloning of a Functional Water Channel From Toad Urinary Bladder Epithelium
Used in 24 Proceeding abstracts
Used in 24 Proceeding abstracts
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Clinical and genetic approaches to the diagnosis of congenital polyuro-polydipsic syndromes
- Clinical presentation of the polyuric and hyperprostaglandinuric salt losing tubulopathies (HPS/aBS) and the therapeutic option with COX inhibitors
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Correction of age-related polyuria by dDAVP: Molecular involvement of aquaporins and urea transporters
- Decrease in urine volume and increase in urine osmolality after SR49059 administration in five adult male patients with X-linked nephrogenic diabetes insipidus
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Long-range transcriptional regulation of the AVPR2 gene
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Mono-ubiquitination and missorting to lysosomes of the Aquaporin-2 water channel mutant AQP2-E258K explains dominant Nephrogenic Diabetes Insipidus
- New insights in water channel physiology revealed by transgenic mouse models
- Novel Roles of Aquaporin Water Channels Revealed by Phenotype Analysis of Knockout Mice
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Structure of V2 vasopressin receptor oligomers: evidence for contact dimer formation
- Structure-Function Analysis of the V2 Vasopressin Receptor
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
Used in 24 Proceeding translations
Used in 24 Proceeding translations
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Contribution of chloride channels in urine concentrating ability
- Decrease in urine volume and increase in urine osmolality after SR49059 administration in five adult male patients with X-linked nephrogenic diabetes insipidus
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- Generation of Germ Line Heterozygous Mice for Aquaporin-2 Conditional Knock-Out and Knock-In Models of NDI
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Long-range transcriptional regulation of the AVPR2 gene
- New insights in water channel physiology revealed by transgenic mouse models
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Recycling of the V2 Vasopressin Receptor
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Structural evolution of the V2 vasopressin receptor in mammals
- Structure of V2 vasopressin receptor oligomers: evidence for contact dimer formation
- Targeting of the V2 Vasopressin Receptor Gene in Mice
- Toward a mouse model of human non-X-linked NDI
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
Used in 187 Term definitions
Used in 187 Term definitions
- B lymphocytes
- B-lymphocytes
- CTL
- E242X
- Fc receptors
- G418
- GPCR mutations
- MALDI-TOF
- MALDI-TOF mass spectrometry
- NDI Abstract of Article: 538
- P and p
- P, p, P, and p
- PDE4D
- Southern blot analysis
- Streptococcus pneumoniae
- T lymphocytes
- absorbed
- adequate
- affinity
- affinity chromatography
- agglutination
- albumin
- alcohol dependence
- anaphylaxis
- antibodies
- antibody
- antiserum
- arbitrary
- area
- autoimmunity
- basal ganglia
- basal nuclei
- biological processes
- biotinylation
- blank
- blockade
- blood group
- bombardment
- cAMP-dependent protein kinase
- capability
- carrier
- cell lysis
- cholesterol
- chromosomal locus
- chromosome banding
- class
- codon
- correction
- countercurrent
- cytokine
- cytolysin
- cytomegalovirus
- cytotoxic T lymphocytes
- cytotoxicity
- delirium
- device
- diameter
- diet
- distribution
- dynamics
- effector
- emotion
- end-organ resistance
- endocrine
- endocrine glands
- enuresis
- enzyme
- enzymes
- evocators
- existence
- expectancy
- facies
- fast
- filter
- fixation
- formula
- function
- gel electrophoresis
- gene
- genes
- genetic code
- genotype
- geometry
- glomus cell
- glycogen storage diseases
- heat capacity
- heavy metal
- helper cells
- homologous
- hormone
- hormones
- hyposensitive
- immune
- immunoassay
- immunoblot analyses
- immunoblot analysis
- immunoblots
- immunoelectrophoresis
- immunoglobulin chains
- immunologic tolerance
- immunoprecipitation
- immunosuppression
- inborn error of metabolism
- inborn errors of metabolism
- incidence
- induction
- insulin
- intermediate filaments
- isoform
- isoforms
- kinetics
- lactose intolerance
- lead
- lichen
- life
- light rays
- lipopolysaccharide
- lipopolysaccharides
- lymphoid cells
- lysis
- lysosomal storage disease
- marker
- mass number
- measurable
- measure
- mechanoreceptors
- medial walls
- mediator
- medullary principal cell
- membrane transport protein
- modality
- modulation
- molecule
- monovalent
- mutant receptors
- neuropathy
- nocturnal enuresis
- nuclease
- nuclei basales
- nucleus
- opsonin
- parameter
- particular
- passive immunization
- pathway
- perfusion
- physical processes
- placebo
- polymerase chain reaction
- precipitate
- principal cell
- principal cells
- process
- processes
- programmed cell death
- project
- prostaglandin
- protein
- protein kinase
- protein kinase C
- proteins
- radioimmunoassay
- radiotelemetry
- ray
- receptor
- recognition
- renal clearance
- renal tubular
- ribonucleic acid
- rubella
- scintiscan
- secondary sex characteristics
- self tolerance
- semiquantitative
- serologic test for syphilis
- signal transduction
- specificity
- spermatozoon
- steroid hormones
- substance-induced mood disorder
- system
- term
- type IV hypersensitivity
- vasopressin
- virus
- zona
- zone



