water channels
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- water channels
-
Channels in a cell membrane that permit passage of water molecules; chemical substances such as vasopressin cause the opening of new channels and increase permeability.
Used in 65 Article abstracts
Used in 65 Article abstracts
- A Novel Mechanism in Recessive Nephrogenic Diabetes Insipidus: Wild-Type Aquaporin-2 Rescues the Apical Membrane Expression of Intracellularly Retained AQP2-P262L
- Activation of the Vasopressin-sensitive Water Permeability Pathway in the Toad Bladder by N-ethyl Maleimide
- Antidiuretic Hormone Modulates Membrane Phosphoproteins in Toad Urinary Bladder and Retrieved Water Channel Containing Apical Membrane Vesicles
- Apical Membrane Vesicles of ADH-stimulated Toad Bladder are Highly Water Permeable
- Aquaporin Molecular Biology and Clinical Abnormalities of the Water Transport Channels
- Aquaporin-2, a Vasopressin-sensitive Water Channel, and Nephrogenic Diabetes Insipidus
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Characterization of Purified Endosomes Containing the Antidiuretic Hormone-Sensitive Water Channel From Rat Renal Papilla
- Cloning and Expression of Apical Membrane Water Channel of Rat Kidney Collecting Tubule
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Cytoplasmic Dilution Induces Antidiuretic Hormone Water Channel Retrieval in Toad Urinary Bladder
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Effect of Water Deprivation and Hypertonic Saline Infusion on Urinary AQP2 Excretion in Healthy Humans
- Endosomes from Kidney Collecting Tubule Cells Contain the Vasopressin-sensitive Water Channel
- Expression of Renal Aquaporins 1, 2, and 3 in a Rat Model of Cisplatin-Induced Polyuria
- Expression of VAMP-2-Like Protein in Kidney Collecting Duct Intracellular Vesicles. Colocalization with Aquaporin-2 Water Channels
- Fate of Antidiuretic Hormone Water Channel Proteins after Retrieval from Apical Membrane
- Fourfold Reduction of Water Permeability in Inner Medullary Collecting Duct of Aquaporin-4 Knockout Mice
- Functional Water Channels Are Present in Clathrin-coated Vesicles from Bovine Kidney but Not from Brain
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Isolation and Characterization of Specialized Regions of Toad Urinary Bladder Apical Plasma Membrane Involved in the Water Permeability Response to Antidiuretic Hormone
- Long-Term Regulation of Collecting Duct Water Permeability: Freeze-Fracture Analysis of Isolated Perfused Tubules
- Long-Term Regulation of Four Renal Aquaporins in Rats
- Long-term Regulation of Aquaporins in the Kidney
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Molecular Aspects of Water Transport
- Molecular Pathogenesis of Nephrogenic Diabetes Insipidus
- Molecular Physiology of Urinary Concentrating Mechanism: Regulation of Aquaporin Water Channels by Vasopressin
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Pathophysiology of Renal Fluid Retention
- Physiology and Pathophysiology of Renal Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Purification and Partial Characterization of Candidate Antidiuretic Hormone Water Channel Proteins of Mr 55,000 and 53,000 from Toad Urinary Bladder
- Quantitation and Topography of Membrane Proteins in Highly Water-Permeable Vesicles From ADH-Stimulated Toad Bladder
- Regulation of Membrane Permeability by Vasopressin; Activation of the Water Permeability Pathway in Toad Urinary Bladder by N-Ethyl-Maleimide
- Renal Aquaporins
- Renal Aquaporins: Key Roles in Water Balance and Water Balance Disorders
- Renal Water Channel Expression in Newborns: Measurement of Urinary Excretion of Aquaporin-2
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of Aquaporins in Water Balance Disorders
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- Structure and Function of Kidney Water Channels
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-Induced Antidiuresis Through Activation of Rho
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Transepithelial Water Flow Regulates Apical Membrane Retrieval in Antidiuretic Hormone-Stimulated Toad Urinary Bladder
- Vasopressin Activates Collecting Duct Urea Transporters and Water Channels by Distinct Physical Processes
- Vasopressin Increases Water Permeability of Kidney Collecting Duct by Inducing Translocation of Aquaporin-CD Water Channels to Plasma Membrane
- Vasopressin Receptor Mutations and Nephrogenic Diabetes Insipidus
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Water Channels
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- Water Channels and Urea Transporters
- Water Transport Across Mammalian Cell Membranes
Used in 3 Article bodies
Used in 3 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 42 Article translations
Used in 42 Article translations
- Activation of the Vasopressin-sensitive Water Permeability Pathway in the Toad Bladder by N-ethyl Maleimide
- Apical Membrane Vesicles of ADH-stimulated Toad Bladder are Highly Water Permeable
- Aquaporin-2 Water Channel Mutations and Nephrogenic Diabetes Insipidus: New Variations on a Theme
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway
- Cytoplasmic Dilution Induces Antidiuretic Hormone Water Channel Retrieval in Toad Urinary Bladder
- Endosomes from Kidney Collecting Tubule Cells Contain the Vasopressin-sensitive Water Channel
- Fate of Antidiuretic Hormone Water Channel Proteins after Retrieval from Apical Membrane
- Functional Water Channels Are Present in Clathrin-coated Vesicles from Bovine Kidney but Not from Brain
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Kinetic Model of Water and Urea Permeability Regulation by Vasopressin in Collecting Duct
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Mechanisms and Regulation of Water Transport in the Kidney
- Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
- Molecular Aspects of Water Transport
- Molecular Mechanisms for the Regulation of Water Transport in Amphibian Epithelia by Antidiuretic Hormone
- Pathophysiology of the Aquaporin Water Channels
- Physiology and Pathophysiology of Aquaporins
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Regulation of Membrane Permeability by Vasopressin; Activation of the Water Permeability Pathway in Toad Urinary Bladder by N-Ethyl-Maleimide
- Relationship Between Vasopressin-Sensitive Water Transport and Plasma Membrane Fluidity in Kidney Collecting Tubule
- Role of Aquaporin Water Channels in Kidney and Lung
- Structure and Function of Kidney Water Channels
- The Aquaporin Family of Molecular Water Channels
- The Aquaporin Family of Water Channels in Kidney: an Update on Physiology and Pathophysiology of Aquaporin-2
- The Cellular Action of Antidiuretic Hormone
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Role of Membrane Turnover in the Water Permeability Response to Antidiuretic Hormone
- Urinary Excretion of Aquaporin-2 in Patients with Diabetes Insipidus
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Water Channels
- Water Channels and Urea Transporters
- Water Channels in Cell Membranes
- Water Transport Across Mammalian Cell Membranes
- cDNA Cloning of a Functional Water Channel From Toad Urinary Bladder Epithelium
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 13 Proceeding abstracts
Used in 13 Proceeding abstracts
- Chemical Chaperones as a Novel Therapeutic Strategy for NDI
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Functional investigations of the vasopressin regulated antidiuretic machinery in single inner medullary collecting duct (IMCD) cells
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Mono-ubiquitination and missorting to lysosomes of the Aquaporin-2 water channel mutant AQP2-E258K explains dominant Nephrogenic Diabetes Insipidus
- N-linked glycosylation is essential for transport of the Aquaporin-2 water channel to the plasma membrane in MDCK cells
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Toward a mouse model of human non-X-linked NDI
Used in 5 Proceeding translations
Used in 5 Proceeding translations
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Regulation and distribution of phosphorylated aquaporin-2 (AQP2) in rat kidney collecting duct principal cells
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus



