basis
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- basis
-
Base: a general anatomical term designating the lowest or fundamental part of a structure or organ, or the part opposite to or distinguished from the apex.
Used in 41 Article abstracts
Used in 41 Article abstracts
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A novel splicing mutation in the V2 vasopressin receptor.
- Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Co-transporter, and Epithelial Sodium Channel
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- CHIP28 Water Channels are Localized in Constitutively Water-Permeable Segments of the Nephron
- Cell-Biologic and Functional Analyses of Five New Aquaporin-2 Missense Mutations that Cause Recessive Nephrogenic Diabetes Insipidus
- Characterization of Purified Endosomes Containing the Antidiuretic Hormone-Sensitive Water Channel From Rat Renal Papilla
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Compound Deletion of the rhoGAP C1 and V2 Vasopressin Receptor Genes in a Patient with Nephrogenic Diabetes Insipidus
- Concentration of Solutes in the Renal Inner Medulla: Interstitial Hyaluronan as a Mechano-Osmotic Transducer
- Congenital Nephrogenic Diabetes Insipidus
- Diabetes Insipidus in Children: Pathophysiology, Diagnosis and Management
- Diabetes Insipidus in Uricase-Deficient Mice: A Model for Evaluating Therapy with Poly(Ethylene Glycol)-Modified Uricase
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Effective Water Clearance and Tonicity Balance: The Excretion of Water Revisited
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Hyponatremia and Hypernatremia
- Identification of Agonist Binding Sites of Vasopressin and Oxytocin Receptors
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Kinetic Model of Water and Urea Permeability Regulation by Vasopressin in Collecting Duct
- Molecular Basis of V2 Vasopressin Receptor/Gs Coupling Selectivity
- Molecular Biology of Diabetes Insipidus
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Purification and Partial Characterization of Candidate Antidiuretic Hormone Water Channel Proteins of Mr 55,000 and 53,000 from Toad Urinary Bladder
- Recent Insights into the Coordinate Regulation of Body Water and Divalent Mineral Ion Metabolism
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Renal Water Channel Expression in Newborns: Measurement of Urinary Excretion of Aquaporin-2
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Segment Specific ENaC Downregulation in Kidney of Rats with Lithium-Induced NDI
- Ser-256 Phosphorylation Dynamics of Aquaporin 2 During Maturation From the Endoplasmic Reticulum to the Vesicular Compartment in Renal Cells
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Molecular Basis of Renal Tubular Transport Disorders
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Unrelated Japanese Kindreds with Nephrogenic Diabetes Insipidus
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- [Clinical Spectrum of Distal Renal Tubular Acidosis and Its Study with Bicarbonate Loading] (Hungarian)
- [Simultaneous Familial Occurrence of Distal Renal Tubular Acidosis, Polycystic Kidney and Nephrogenic Diabetes Insipidus] (Hungarian)
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 10 Article bodies
Used in 10 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Nephrogenic Diabetes Insipidus in a Patient Taking Cidofovir
- Nephrogenic Diabetes Insipidus--Prodromal Phase of Multiple Myeloma
- Nephrogenic Diabetes Insipidus: A Cause of Severe Nonobstructive Urinary Tract Dilatation
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 51 Article translations
Used in 51 Article translations
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Low-Affinity Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- A Variant of Nephrogenic Diabetes Insipidus: V2 Receptor Abnormality Restricted to the Kidney
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- Aquaporin-2, a Vasopressin-sensitive Water Channel, and Nephrogenic Diabetes Insipidus
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Correlation between Magnetic Resonance Imaging of Posterior Pituitary and Neurohypophyseal Function in Children with Diabetes Insipidus
- Detection of Skewed X-Inactivation in Two Female Carriers of Vasopressin Type 2 Receptor Gene Mutation
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Emergency Treatment of Lithium-Induced Diabetes Insipidus with Nonsteroidal Anti-Inflammatory Drugs
- Expression Cloning of the Human V2 Vasopressin Receptor
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- G-Protein-Coupled Receptors in Endocrine Disease
- Hereditary Vasopressin Resistance in Man and Mouse
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Homer Smith: His Contribution to the Practice of Nephrology
- Inherited Diseases of the Kidney
- Kinetic Model of Water and Urea Permeability Regulation by Vasopressin in Collecting Duct
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Mechanism of Lithium-Induced Polyuria in the Rat
- Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
- Molecular Aspects of Vasopressin Receptor Function
- Molecular Biology of Diabetes Insipidus
- Molecular Insights into the Pathogenesis of Inherited Renal Tubular Disorders
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2-Receptor Gene in Three Families of Italian Descent with Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet)
- Nephrogenic Diabetes Insipidus, Thiazide Treatment and Renal Cell Carcinoma
- Nephrogenic Diabetes Insipidus--Prodromal Phase of Multiple Myeloma
- Nephrogenic Diabetes Insipidus: A Cause of Severe Nonobstructive Urinary Tract Dilatation
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Normal Fibrinolytic Responses to 1-Desamino-8-D-Arginine Vasopressin in Patients with Nephrogenic Diabetes Insipidus Caused by Mutations in the Aquaporin 2 Gene
- Novel Mutations in the V2 Vasopressin Receptor Gene in Two Pedigrees with Congenital Nephrogenic Diabetes Insipidus
- Pathophysiology of the Aquaporin Water Channels
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Reconstitution of a Regulated Transepithelial Water Pathway in Cells Transfected with AQP2 and an AQP1/AQP2 Hybrid Containing the AQP2-C Terminus
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Role of Aquaporins in Water Balance Disorders
- Rolipram, a Phosphodiesterase Inhibitor, in the Treatment of Two Male Patients with Congenital Nephrogenic Diabetes Insipidus
- Successful Treatment with Hydrochlorothiazide and Amiloride in an Infant with Congenital Nephrogenic Diabetes Insipidus
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Clinical Importance of the Urinary Excretion of Aquaporin-2
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- Vasopressin Effects on Urea and H20 Transport in Inner Medullary Collecting Duct Subsegments
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Water Channels and Urea Transporters
- Water Channels in Health and Disease
Used in 3 Faq answers
Used in 3 Faq answers
- Could you explain, in layman's terms, what happens genetically when a father, daughter, and male child of the daughter all have DI?
- How is NDI treated?
- My son's male cousin who is 3 years old was just diagnosed with Diabetes Insipidus. They are trying to find out if there is a genetic link. My son who is 21 years old now, has frequent urination, up at least 7 times throughout the night to void. He states
Used in 18 Proceeding abstracts
Used in 18 Proceeding abstracts
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Cotransporter and Epithelial Sodium Channel
- Cell biological and functional analysis of five new Aquaporin-2 gene missense mutations in recessive Nephrogenic Diabetes Insipidus
- Clinical and genetic approaches to the diagnosis of congenital polyuro-polydipsic syndromes
- Congenital (present a birth) severe diabetes insipidus. Most patients have nephrogenic diabetes insipidus (NDI), but some patients have autosomal recessive central (neurogenic) diabetes insipidus
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Identification of sequence determinants that direct different intracellular folding pathways for kidney aquaporins
- Modulation of aquaporin-2 expression in primary cultured rat inner medullary collecting duct (IMCD) cells
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- New insights in water channel physiology revealed by transgenic mouse models
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- The Low Sodium Diet for Nephrogenic Diabetes Insipidus
- The last fifty years; a retrospective on NDI
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- V2 Vasopressin Receptors in NDI: Where did they go?
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
Used in 3 Proceeding translations
Used in 3 Proceeding translations
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- Modulation of aquaporin-2 expression in primary cultured rat inner medullary collecting duct (IMCD) cells
- Mono-ubiquitination and missorting to lysosomes of the Aquaporin-2 water channel mutant AQP2-E258K explains dominant Nephrogenic Diabetes Insipidus
Used in 44 Term definitions
Used in 44 Term definitions
- Clostridium
- Lyon hypothesis
- NDI Abstract of Article: 510
- Streptococcus pneumoniae
- acetone
- adenine
- alloy
- casein
- classification
- classified
- differentiate
- differentiated
- enteroendocrine cells
- epithelium
- establish
- foundation
- gel electrophoresis
- genetic code
- ground
- histamine
- hypothesis
- hypothesis test
- influenza virus
- infrared
- kappa
- lymphocyte
- lymphocytes
- lyonization
- magnitude
- mental deficiency
- metric
- nuclease
- polyacrylamide gel electrophoresis
- prejudice
- pyran
- respiratory syncytial viruses
- serum globulins
- sex
- sibship
- sucrose
- taxonomy
- teichoic acid
- teichoic acids
- virus