chemical
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- chemical
-
1. Of, or pertaining to, chemistry.
2. A substance composed of chemical elements, or obtained by chemical processes.
Used in 9 Article abstracts
Used in 9 Article abstracts
- Appropriate Polarization Following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-Linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
- Compound Deletion of the rhoGAP C1 and V2 Vasopressin Receptor Genes in a Patient with Nephrogenic Diabetes Insipidus
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
- Nephrogenic diabetes insipidus.
- Pharmacological Chaperones: Potential Treatment for Conformational Diseases
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Rescue of a Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutant by Cell-Penetrating Peptides
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 28 Article translations
Used in 28 Article translations
- A Congenital Renal Tubular Defect
- A Mouse Model to Test the in vivo Efficacy of Chemical Chaperones
- A Role for K268 in V2R Folding
- Activation of the Vasopressin-sensitive Water Permeability Pathway in the Toad Bladder by N-ethyl Maleimide
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Rescue of the Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutants G185C and R202C by a Second Site Suppressor Mutation
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Kinetic Model of Water and Urea Permeability Regulation by Vasopressin in Collecting Duct
- Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
- Pemetrexed-Induced Acute Renal Failure, Nephrogenic Diabetes Insipidus, and Renal Tubular Acidosis in a Patient with Non-Small Cell Lung Cancer
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Pharmacological Chaperones: Potential Treatment for Conformational Diseases
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Polyuria in Childhood
- Relief of Nocturnal Enuresis by Desmopressin is Kidney and Vasopressin Type 2 Receptor Independent
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Vasopressin Type 2 Receptor Gene. Chromosomal Localization and Its Role in Nephrogenic Diabetes Insipidus
- Therapeutic Potential of Vasopressin Receptor Antagonists
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 6 Proceeding abstracts
Used in 6 Proceeding abstracts
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
Used in 10 Proceeding translations
Used in 10 Proceeding translations
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- A pharmacological chaperone acting at the V2-vasopressin receptor offers a treatment for Nephrogenic Diabetes Insipidus
- Calcineurin A-alpha knockout is a new model of nephrogenic diabetes insipidus
- Decrease in urine volume and increase in urine osmolality after SR49059 administration in five adult male patients with X-linked nephrogenic diabetes insipidus
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
Used in 151 Term definitions
Used in 151 Term definitions
- 1H-imidazole-4-ethanamine
- D-fructose
- G protein-coupled receptors
- G-protein coupled receptors
- G-protein-coupled receptors
- acid
- actinic
- actinium
- action potential
- agent
- americium
- amino
- anabolism
- analog
- antibiotic
- antibiotics
- atomic number
- biotransformation
- bleached
- blockade
- buffer
- californium
- cancer
- carbonic acid
- carrier
- challenge
- chaperone
- chemical
- chemical compound
- chemical reaction
- chemical stimuli
- chemicals
- chemiluminescence
- chemoreceptor
- chemotherapy
- chiropractic
- cobalamin
- coefficient
- compound
- congenital defect
- covalence
- crystal
- curing
- curium
- cyclic
- cysteine
- cytoplasm
- defecation
- deoxy
- derivative
- derivatives
- differentiation
- digest
- digestion
- direct current
- dissolution
- downregulation
- drug
- electrochemical
- electron
- element
- enzyme inhibitors
- eradicating
- evocators
- extraembryonic membranes
- factor
- feed additive
- field block
- fixation
- fructose
- functional group
- galvanism
- generic
- generically
- glycine
- histamine
- histochemical
- histochemistry
- hormone
- hormones
- hydrocarbon
- hydroxyl
- immunoassay
- immunology
- inactivation
- incubation
- inductor
- inhibitor
- inhibitors
- intoxication
- isolation
- isomerism
- isotope
- isozyme
- lawrencium
- lithium
- mass number
- mechanism
- mechanisms
- mediator
- metabolism
- methyl
- methyl group
- molecule
- negative electrons
- organic
- organic compound
- pentavalent
- periodic table
- pharmacodynamics
- pharmacopeia
- photochemical
- photosynthesis
- physical chemistry
- physiology
- poison
- poisons
- polymodal nociceptors
- pressor
- radical
- radioactive tracer
- radioactivity
- react
- reacted
- reaction
- reduced
- releasing factors
- renal water channel
- saturated
- semisynthetically
- sequestered
- signal transduction
- signaling
- solution
- solvation
- substitution
- synapse
- synapsing
- transferase
- ultraviolet
- unstable
- up-regulate
- upregulation
- urinalysis
- vaporization
- vasopressin-sensitive water channel
- vitalism
- vitamin B12
- vitamin B12
- water channel
- water channels



