concentrate
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- concentrate
-
1. To bring to a common center; to gather together at one point.
2. To increase the strength by diminishing the bulk of, as of a liquid; to condense.
3. A drug or other preparation that has been strengthened by the evaporation of its non-active parts.
Used in 32 Article abstracts
Used in 32 Article abstracts
- A Novel Deletion Mutation in the Arginine Vasopressin Receptor 2 Gene and Skewed X Chromosome Inactivation in a Female Patient with Congenital Nephrogenic Diabetes Insipidus
- A Novel Mechanism in Recessive Nephrogenic Diabetes Insipidus: Wild-Type Aquaporin-2 Rescues the Apical Membrane Expression of Intracellularly Retained AQP2-P262L
- Acquired Nephrogenic Diabetes Insipidus Secondary to Distal Renal Tubular Acidosis and Nephrocalcinosis Associated with Sjogren's Syndrome
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- Cell-Biologic and Functional Analyses of Five New Aquaporin-2 Missense Mutations that Cause Recessive Nephrogenic Diabetes Insipidus
- Congenital Nephrogenic Diabetes Insipidus
- Defective processing and trafficking of water channels in nephrogenic diabetes insipidus.
- Desmopressin for Nocturnal Enuresis in Nephrogenic Diabetes Insipidus
- Development of Urinary Concentrating Capacity: Role of Aquaporin-2
- Development of Water Transport in the Collecting Duct
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Generation and Phenotype of Mice Harboring a Nonsense Mutation in the V2 Vasopressin Receptor Gene
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus in Mice Lacking Aquaporin-3 Water Channels
- Nephrogenic Diabetes Insipidus in Sibling Colts
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Nephrogenic diabetes insipidus.
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Routing of the aquaporin-2 water channel in health and disease.
- The Molecular Basis of Renal Tubular Transport Disorders
- The V2 vasopressin receptor mutations and fluid homeostasis.
- Treatment of Nephrogenic Diabetes Insipidus with Hydrochlorothiazide and Amiloride
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- Water Transport in the Kidney and Nephrogenic Diabetes Insipidus
- [Hereditary Nephrogenic Diabetes Insipidus] (French)
Used in 7 Article bodies
Used in 7 Article bodies
- A Novel Polymorphism in the Coding Region of the Vasopressin Type 2 Receptor Gene
- Hereditary Vasopressin Resistance in Man and Mouse
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus Following High Dose Epirubicin Chemotherapy for Metastatic Soft Tissue Sarcoma [Letter]
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 181 Article translations
Used in 181 Article translations
- 1-Desamino-8-D-Arginine Vasopressin (DDAVP) in Patients with Congenital Nephrogenic Diabetes Insipidus
- A Family Case of Nephrogenic Diabetes Insipidus
- A Low-Affinity Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- A Mouse Model to Test the in vivo Efficacy of Chemical Chaperones
- A Novel Deletion Mutation in the Arginine Vasopressin Receptor 2 Gene and Skewed X Chromosome Inactivation in a Female Patient with Congenital Nephrogenic Diabetes Insipidus
- A Null Mutation in the Vasopressin V2 Receptor Gene (AVPR2) Associated with Nephrogenic Diabetes Insipidus in the Hopewell Kindred
- A Role for K268 in V2R Folding
- A Variant of Nephrogenic Diabetes Insipidus: V2 Receptor Abnormality Restricted to the Kidney
- Aggravation of Subclinical Diabetes Insipidus During Pregnancy
- Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus
- Altered Expression of COX-1, COX-2, and mPGES in Rats with Nephrogenic and Central Diabetes Insipidus
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- Amphotericin B Decreases Adenylyl Cyclase Activity and Aquaporin-2 Expression in Rat Kidney
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Aquaporin-2 Water Channel Mutations and Nephrogenic Diabetes Insipidus: New Variations on a Theme
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Assignment of the Human Gene for the Water Channel of Renal Collecting Duct Aquaporin 2 (AQP2) to Chromosome 12 Region q12-->q13
- Autosomal Recessive Nephrogenic Diabetes Insipidus Caused by an Aquaporin-2 Mutation
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
- Biology and Genetics of Inherited Renal Tubular Disorders (editorial)
- Brief Report: A Molecular Defect in the Vasopressin V2-Receptor Gene Causing Nephrogenic Diabetes Insipidus
- Brief Report: A Mutation in the Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- Cellular Mechanism of Lithium-Induced Nephrogenic Diabetes Insipidus in Rats
- Changes of Rat Kidney AQP2 and Na,K-ATPase mRNA Expression in Lithium-Induced Nephrogenic Diabetes Insipidus
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Cloning, Characterization, and Chromosomal Mapping of Human Aquaporin of Collecting Duct
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Congenital Nephrogenic Diabetes Insipidus
- Congenital Nephrogenic Diabetes Insipidus in an Adult
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Desmopressin for Nocturnal Enuresis in Nephrogenic Diabetes Insipidus
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Diabetes Insipidus (Hendy, Bichet)
- Diabetes Insipidus (Robertson)
- Differential Diagnosis and Pathophysiology of Diabetes Insipidus
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- Effect of DDAVP on Nocturnal Enuresis in a Patient with Nephrogenic Diabetes Insipidus
- Effect of an Acute Oral Ibuprofen Intake on Urinary Aquaporin-2 Excretion in Healthy Humans
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- Emergency Treatment of Lithium-Induced Diabetes Insipidus with Nonsteroidal Anti-Inflammatory Drugs
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evaluation and Management of Diabetes Insipidus
- Evidence for Intact V1-vasopressin Receptors in Congenital Nephrogenic Diabetes Insipidus
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Familial Nephrogenic Diabetes Insipidus: Report of Two Families
- Fate of Antidiuretic Hormone Water Channel Proteins after Retrieval from Apical Membrane
- Fibrinolytic Responses to 1-desamino-8-D-arginine-vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Foscarnet Alters Antidiuretic Hormone-Mediated Transport
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- G-Protein-Coupled Receptors in Endocrine Disease
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- GS-Activating Receptors: Modes of Transmembrane Signalling and Genetic Defects
- Genetic Restoration of Aldose Reductase to the Collecting Tubules Restores Maturation of the Urine Concentrating Mechanism
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Hereditary Nephrogenic Diabetes Insipidus
- Hereditary Nephrogenic Diabetes Insipidus and Bilateral Nonobstructive Hydronephrosis
- Hereditary Vasopressin Resistance in Man and Mouse
- Heterogeneous AVPR2 Gene Mutations in Congenital Nephrogenic Diabetes Insipidus
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Hyperuricemia as a Clue for Central Diabetes Insipidus (Lack of V1 Effect) in the Differential Diagnosis of Polydipsia
- Hypokalemic Nephropathy and Nephrogenic Diabetes Insipidus Due to Excessive Consumption of a Soft Drink
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Induction of Intramembranous Particle Clusters in Mice with Nephrogenic Diabetes Insipidus
- Inherited Diseases of the Kidney
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Intrafamilial Phenotype Variability in Nephrogenic Diabetes Insipidus
- Kidney Damage in Long-Term Lithium Patients: A Cross-Sectional Study of Patients with 15 Years or More on Lithium
- Large-Scale Purification of Functional Recombinant Human Aquaporin-2
- Lithium Nephrotoxicity
- Lithium-Induced Diabetes Insipidus in a Surgical Patient: Report of a Case and Review of the Literature
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Intravenous Ketorolac
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Lithium-induced Nephrogenic Diabetes Insipidus
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Molecular Biology of Diabetes Insipidus
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Identification of the Gene Responsible for Congenital Nephrogenic Diabetes Insipidus
- Molecular Insights into the Pathogenesis of Inherited Renal Tubular Disorders
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular and Cellular Biology of Vasopressin and Oxytocin Receptors and Action in the Kidney
- Molecular and Cellular Defects in Nephrogenic Diabetes Insipidus
- Mutations and Diseases of G Protein Coupled Receptors
- Mutations in the V2 Vasopressin Receptor Gene are Associated with X-linked Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2 Receptor and Aquaporin-2 Genes in 12 Families with Congenital Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus (Bichet)
- Nephrogenic Diabetes Insipidus Associated with Foscarnet - A Case Report [letter]
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Nephrogenic Diabetes Insipidus in North America. The Hopewell Hypothesis
- Nephrogenic Diabetes Insipidus in Sibling Colts
- Nephrogenic Diabetes Insipidus in a Lethargic Lithium-Treated Patient
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Nephrogenic Diabetes Insipidus: Causes Revealed
- Nephrogenic Diabetes Insipidus: Clinical Symptoms, Pathogenesis, Genetics and Treatment
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Normal Fibrinolytic Responses to 1-Desamino-8-D-Arginine Vasopressin in Patients with Nephrogenic Diabetes Insipidus Caused by Mutations in the Aquaporin 2 Gene
- Novel Mutations in the V2 Vasopressin Receptor Gene of Patients with X-Linked Nephrogenic Diabetes Insipidus
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Pathogenesis and Treatment of Autosomal-Dominant Nephrogenic Diabetes Insipidus Caused by an Aquaporin 2 Mutation
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Patients with Autosomal Nephrogenic Diabetes Insipidus Homozygous for Mutations in the Aquaporin 2 Water-Channel Gene
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Physiology and Pathophysiology of Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Polyuria and Polydipsia. Problems Associated with Patient Evaluation
- Polyuria in Childhood
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Recent Advances in Water Transport
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Relief of Nocturnal Enuresis by Desmopressin is Kidney and Vasopressin Type 2 Receptor Independent
- Renal Aquaporins
- Renal Function On and Off Lithium in Patients Treated with Lithium for 15 Years or More. A Controlled, Prospective Lithium-Withdrawal Study
- Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- Role of Aquaporins in Water Balance Disorders
- Role of Inner Medullary Collecting Duct NaCl Transport in Urinary Concentration
- Role of cAMP-Phosphodiesterase Isozymes in Pathogenesis of Murine Nephrogenic Diabetes Insipidus
- Rolipram, a Phosphodiesterase Inhibitor, in the Treatment of Two Male Patients with Congenital Nephrogenic Diabetes Insipidus
- Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
- Severely Impaired Urine-Concentrating Ability in Mice Lacking the CLC-K1 Chloride Channel
- Six Novel Mutations in the Vasopressin V2 Receptor Gene Causing Nephrogenic Diabetes Insipidus
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- Structure and Chromosomal Localization of the Human Antidiuretic Hormone Receptor Gene
- Successful Treatment with Hydrochlorothiazide and Amiloride in an Infant with Congenital Nephrogenic Diabetes Insipidus
- The Aquaporin Family of Molecular Water Channels
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Aquaporin Family of Water Channels in Kidney: an Update on Physiology and Pathophysiology of Aquaporin-2
- The Clinical Importance of the Urinary Excretion of Aquaporin-2
- The Hydrophobic Amino Acid Residues in the Membrane-Proximal C Tail of the G Protein-Coupled Vasopressin V2 Receptor are Necessary for Transport-Competent Receptor Folding
- The Ins and Outs of Aquaporin-2 Trafficking
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Transient Nephrogenic Diabetes Insipidus Accompanied by Possible Psychogenic Polydipsia
- Treatment of Nephrogenic Diabetes Insipidus with Hydrochlorothiazide and Amiloride
- Two Novel Mutations in the Aquaporin-2 and the Vasopressin V2 Receptor Genes in Patients with Congenital Nephrogenic Diabetes Insipidus
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Patients with Congenital Nephrogenic Diabetes Insipidus
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Unrelated Japanese Kindreds with Nephrogenic Diabetes Insipidus
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Upregulation of Urea Transporter UT-A2 and Water Channels AQP2 and AQP3 in Mice Lacking Urea Transporter UT-B
- Urinary Concentrating Defect in Experimental Hemochromatosis
- Urinary Concentrating Mechanism: The Role of the Inner Medulla
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- Urinary Excretion of Aquaporin-2 in Patients with Diabetes Insipidus
- Use of T1-weighted MR Imaging to Differentiate between Primary Polydipsia and Central Diabetes Insipidus
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- Water Channels in Health and Disease
- X-Linked Nephrogenic Diabetes Insipidus Mutations in North America and the Hopewell Hypothesis
- Xanthopterin-Induced Renal Dysfunction: A Reversible Model of Crystal Nephropathy
Used in 4 Faq answers
Used in 4 Faq answers
- What causes NDI?
- Could you explain, in layman's terms, what happens genetically when a father, daughter, and male child of the daughter all have DI?
- How do each of the three most commonly prescribed medications for NDI treatment (chlorothiazide/hydrochlorothiazide, amiloride, and indomethacin) work in the body?
- How do the medications interact with each other?
Used in 21 Proceeding abstracts
Used in 21 Proceeding abstracts
- Renal medullary gene expression in aquaporin-1 null mice
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- A mouse model for X-linked nephrogenic diabetes insipidus
- An impaired routing of wild type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
- Cell biological and functional analysis of five new Aquaporin-2 gene missense mutations in recessive Nephrogenic Diabetes Insipidus
- Chemical Chaperones as a Novel Therapeutic Strategy for NDI
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Clinical Phenotype and Molecular Characterization of A Mutant V2 Receptor Associated with Partial Congenital Nephrogenic Diabetes Insipidus
- Defective urinary concentrating function in transgenic mice lacking urea transporter UT-B
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- Gene Mutation Analysis of NDI patients in Japan
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Nephrogenic Diabetes Insipidus in mice lacking aquaporin-3 water channels
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- Pitfalls in the Differential Diagnosis of Nephrogenic Diabetes Insipidus.
- Production and purification of Aquaporin-2 and Vasopressin 2 Receptor: towards elucidation of the structure
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Two new Aquaporin-2 mutations responsible for Congenital Nephrogenic Diabetes Insipidus
Used in 19 Proceeding translations
Used in 19 Proceeding translations
- Renal medullary gene expression in aquaporin-1 null mice
- Calcineurin A-alpha knockout is a new model of nephrogenic diabetes insipidus
- Chemical Chaperones as a Novel Therapeutic Strategy for NDI
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Contribution of chloride channels in urine concentrating ability
- Defective urinary concentrating function in transgenic mice lacking urea transporter UT-B
- Expressional alteration of sodium transporter in the thick ascending limb of Henle and urinary concentration
- Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus: molecular basis of a mild clinical phenotype.
- Growth in males with (well-managed) nephrogenic diabetes insipidus
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus in mice lacking aquaporin-3 water channels
- New insights in water channel physiology revealed by transgenic mouse models
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- The Ontogeny and Regulation of AQP2 Gene Expression in the Ovine Fetal Kidney
- Urinary Concentrating Defect in Mice With Selective Deletion of Collecting-Duct Urea Transporter Isoforms, UT-A1 and UT-A3
- V2 vasopressin receptor-deficient mouse model: Pathophysiological changes and therapeutical implications
- Variations in clinical phenotype associated with different mutations of the V2 receptor gene in X-linked recessive congenital nephrogenic DI (xCNDI)
- Vasopressin-Independent Regulation of Aquaporin-2 Protein



