data
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- data
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The material or collection of facts on which a discussion, a calculation, or an inference is based.
Used in 82 Article abstracts
Used in 82 Article abstracts
- A Compartmental Model Predicts that Dietary Potassium Affects Lithium Dynamics in Rats
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Null Mutation in the Vasopressin V2 Receptor Gene (AVPR2) Associated with Nephrogenic Diabetes Insipidus in the Hopewell Kindred
- A Role for K268 in V2R Folding
- A historical cohort study of kidney damage in long-term lithium patients: continued surveillance needed.
- Activation of the Vasopressin-sensitive Water Permeability Pathway in the Toad Bladder by N-ethyl Maleimide
- Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Apical Extracellular Calcium/Polyvalent Cation-sensing Receptor Regulates Vasopressin-elicited Water Permeability in Rat Kidney Inner Medullary Collecting Duct
- Aquaporin-2 Expression in Primary Cultured Rat Inner Medullary Collecting Duct Cells
- Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
- Causes of Reversible Nephrogenic Diabetes Insipidus: A Systematic Review
- Characterization of Purified Endosomes Containing the Antidiuretic Hormone-Sensitive Water Channel From Rat Renal Papilla
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Clinical Presentation and Follow-Up of 30 Patients with Congenital Nephrogenic Diabetes Insipidus
- Cyclic AMP is Sufficient for Triggering the Exocytic Recruitment of Aquaporin-2 in Renal Epithelial Cells
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Disease-Causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway
- Dissociation Between Urine Osmolality and Urinary Excretion of Aquaporin-2 in Healthy Volunteers
- Dual Influence of Aldosterone on AQP2 Expression in Cultured Renal Collecting Duct Principal Cells
- Experimental Tests of Three-Dimensional Model of Urinary Concentrating Mechanism
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking.
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Hyperuricemia as a Clue for Central Diabetes Insipidus (Lack of V1 Effect) in the Differential Diagnosis of Polydipsia
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Inheritance of Mutations in the V2 Receptor Gene in Thirteen Families with Nephrogenic Diabetes Insipidus
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Kidney Damage in Long-Term Lithium Patients: A Cross-Sectional Study of Patients with 15 Years or More on Lithium
- Lithium Revisited
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Metoprine-induced Thirst and Diuresis in Wistar Rats
- Molecular Aspects of Water Transport
- Molecular Genetic Study of Congenital Nephrogenic Diabetes Insipidus and Rescue of Mutant Vasopressin V2 Receptor by Chemical Chaperones
- Molecular Mechanisms of Urea Transport
- Mutational Analysis of the Relative Orientation of Transmembrane Helices I and VII in G Protein-Coupled Receptors
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus and Renal Tubular Acidosis Secondary to Foscarnet Therapy
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Novel Vasopressin Type 2 (AVPR2) Gene Mutations in Brazilian Nephrogenic Diabetes Insipidus Patients
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Purification and Partial Characterization of Candidate Antidiuretic Hormone Water Channel Proteins of Mr 55,000 and 53,000 from Toad Urinary Bladder
- Quantitation and Topography of Membrane Proteins in Highly Water-Permeable Vesicles From ADH-Stimulated Toad Bladder
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Recent Advances in Water Transport
- Recent Insights into the Coordinate Regulation of Body Water and Divalent Mineral Ion Metabolism
- Regulation of V2 Vasopressin Receptor Degradation by Agonist Promoted Ubiquitination
- Relief of Nocturnal Enuresis by Desmopressin is Kidney and Vasopressin Type 2 Receptor Independent
- Renal Haemodynamics, Sodium and Water Reabsorption During Continuous Intravenous Infusion of Recombinant Interleukin-2
- Rescue of a Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutant by Cell-Penetrating Peptides
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Rho Inhibits cAMP-Induced Translocation of Aquaporin-2 into the Apical Membrane of Renal Cells
- Role of the Cytoplasmic Termini in the Sorting and Shuttling of the Aquaporin-2 Water Channel
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
- Structure and Function of Kidney Water Channels
- The Ins and Outs of Aquaporin-2 Trafficking
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Prostaglandin E2 Analogue Sulprostone Antagonizes Vasopressin-Induced Antidiuresis Through Activation of Rho
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Vasopressin and Oxytocin Receptors Coupled to Ca2+ Mobilization in Rat Inner Medullary Collecting Duct
- Vasopressin- and cAMP-Induced Changes in Ultrastructure of Isolated Perfused Inner Medullary Collecting Ducts
- Vasopressin-elicited Water and Urea Permeabilities are Altered in IMCD in Hypercalcemic Rats
- Water Channels
- [Expression of Aquaporin in Rats' Endolymphatic Sac and Kidney and the Effect of Anti-Diuretic Hormone on the Expression of Aquaporin]
- [Recent Advances in Vasopressin Receptors and Signal Transduction System] (Japanese)
Used in 12 Article bodies
Used in 12 Article bodies
- A Novel Polymorphism in the Coding Region of the Vasopressin Type 2 Receptor Gene
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Nephrogenic Diabetes Insipidus in North America. The Hopewell Hypothesis
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- Persistent Nephrogenic Diabetes Insipidus Following Lithium Therapy
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Risk Factors for Ifosfamide Nephrotoxicity in Children
Used in 25 Article translations
Used in 25 Article translations
- A Low-Affinity Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- A Null Mutation in the Vasopressin V2 Receptor Gene (AVPR2) Associated with Nephrogenic Diabetes Insipidus in the Hopewell Kindred
- A Role for K268 in V2R Folding
- Changes of Rat Kidney AQP2 and Na,K-ATPase mRNA Expression in Lithium-Induced Nephrogenic Diabetes Insipidus
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- GS-Activating Receptors: Modes of Transmembrane Signalling and Genetic Defects
- Genetic Restoration of Aldose Reductase to the Collecting Tubules Restores Maturation of the Urine Concentrating Mechanism
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- High Proton Flux through Membranes Containing Antidiuretic Hormone Water Channels
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inheritance of Mutations in the V2 Receptor Gene in Thirteen Families with Nephrogenic Diabetes Insipidus
- Mechanism of Vasopressin Action in the Renal Collecting Duct
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Role of Sodium Depletion in Acute Antidiuretic Effect of Bendroflumethiazide in Rats with Nephrogenic Diabetes Insipidus
- The Hydrophobic Amino Acid Residues in the Membrane-Proximal C Tail of the G Protein-Coupled Vasopressin V2 Receptor are Necessary for Transport-Competent Receptor Folding
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Urinary Concentrating Mechanism: The Role of the Inner Medulla
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
Used in 30 Proceeding abstracts
Used in 30 Proceeding abstracts
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- Analysis of molecular mechanisms causing V2 vasopressin receptor dysfunction in four patients with X-linked nephrogenic diabetes insipidus
- Aquaporin 2-containing Apical Membrane Endosomes (AQP-2 Endosomes) Possess a Multiprotein Signaling Complex
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Complete deletions of the vasopressin type 2 receptor gene in nephrogenic diabetes insipidus
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Contribution of chloride channels in urine concentrating ability
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Follow up of NDI patients and presentation of a case report
- Functional rescue of three vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus by a second site suppressor mutation
- Growth in males with (well-managed) nephrogenic diabetes insipidus
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Naturally occurring and in vitro mutations defining the role of the NPXXY motif in the vasopressin V2 receptor
- Nephrogenic Diabetes Insipidus Mutation Database
- Novel Roles of Aquaporin Water Channels Revealed by Phenotype Analysis of Knockout Mice
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Structure-Function Analysis of the V2 Vasopressin Receptor
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- Thirteen Large Deletions/Rearrangements of the AVPR2 Gene Causing X-linked Nephrogenic Diabetes Insipidus
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
Used in 8 Proceeding translations
Used in 8 Proceeding translations
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Contribution of chloride channels in urine concentrating ability
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Follow up of NDI patients and presentation of a case report
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Thirteen Large Deletions/Rearrangements of the AVPR2 Gene Causing X-linked Nephrogenic Diabetes Insipidus



