gastrin
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- gastrin
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Any of several polypeptide hormones released from peptidergic fibers in the vagus nerve and from G cells in the pyloric glands in the gastric antrum. Forms include little gastrins (G17), with chain lengths of 17 amino acids, big gastrins (G34), and minigastrins (G14). Gastrin stimulates secretion of gastric acid (causing contraction of the lower esophageal sphincter and modifying gastric and esophageal motility), increases growth of acid-secreting mucosa cells, and weakly stimulates secretion of pancreatic enzymes and gallbladder contraction.




Used in 1 Article abstract
Used in 1 Article abstract