human
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- human
Used in 82 Article abstracts
Used in 82 Article abstracts
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- Agonist and Antagonist-Dependent Internalization of the Human Vasopressin V2 Receptor
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- Antidiuretic Action of Oxytocin is Associated with Increased Urinary Excretion of Aquaporin-2
- Apical Extracellular Calcium/Polyvalent Cation-sensing Receptor Regulates Vasopressin-elicited Water Permeability in Rat Kidney Inner Medullary Collecting Duct
- Aquaporin Expression in Normal Human Kidney and in Renal Disease
- Aquaporin Molecular Biology and Clinical Abnormalities of the Water Transport Channels
- Aquaporins in Complex Tissues: Distribution of Aquaporins 1-5 in Human and Rat Eye
- Assignment of the Human Gene for the Water Channel of Renal Collecting Duct Aquaporin 2 (AQP2) to Chromosome 12 Region q12-->q13
- Autosomal Recessive Nephrogenic Diabetes Insipidus Caused by an Aquaporin-2 Mutation
- Causes of Reversible Nephrogenic Diabetes Insipidus: A Systematic Review
- Characterization of SR 121463A, A Highly Potent and Selective, Orally Active Vasopressin V2 Receptor Antagonist
- Cloned Human Aquaporin-1 is a Cyclic GMP-gated Ion Channel
- Cloning, Characterization, and Chromosomal Mapping of Human Aquaporin of Collecting Duct
- Comparative Mapping on the Mouse and Human X Chromosomes of a Human cDNA Clone Encoding the Vasopressin Renal-Type Receptor (AVP2R)
- Compound Deletion of the rhoGAP C1 and V2 Vasopressin Receptor Genes in a Patient with Nephrogenic Diabetes Insipidus
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Detection of Skewed X-Inactivation in Two Female Carriers of Vasopressin Type 2 Receptor Gene Mutation
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Diabetes Insipidus in Uricase-Deficient Mice: A Model for Evaluating Therapy with Poly(Ethylene Glycol)-Modified Uricase
- Diffusion in the Endoplasmic Reticulum of an Aquaporin-2 Mutant Causing Human Nephrogenic Diabetes Insipidus
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Disease-Causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway
- Effect of Water Deprivation and Hypertonic Saline Infusion on Urinary AQP2 Excretion in Healthy Humans
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Folding and Cell Surface Expression of the Vasopressin V2 Receptor: Requirement of the Intracellular C-terminus
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Rescue of the Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutants G185C and R202C by a Second Site Suppressor Mutation
- Genetics of Vasopressin Receptors
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Human Platelet Fraction Arginine-Vasopressin. Potential Physiological Role
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Isolation of Human aquaporin-CD Gene
- Large-Scale Purification of Functional Recombinant Human Aquaporin-2
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Mild Nephrogenic Diabetes Insipidus Caused by Foxa1 Deficiency
- Misfolded Vasopressin V2 Receptors Caused by Extracellular Point Mutations Entail Congenital Nephrogenic Diabetes Insipidus.
- Molecular Aspects of Vasopressin Receptor Function
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular and Cellular Biology of Vasopressin and Oxytocin Receptors and Action in the Kidney
- Mutations in the Vasopressin Type 2 Receptor Gene (AVPR2) Associated with Nephrogenic Diabetes Insipidus
- Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Pharmacological Chaperones: A New Twist on Receptor Folding
- Platelet Vasopressin Receptors in Patients With Congenital Nephrogenic Diabetes Insipidus
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Properties of a New Radioiodinated Antagonist for Human Vasopressin V2 and V1a Receptors
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Purification and Partial Characterization of Candidate Antidiuretic Hormone Water Channel Proteins of Mr 55,000 and 53,000 from Toad Urinary Bladder
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Renal Water Channel Expression in Newborns: Measurement of Urinary Excretion of Aquaporin-2
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Sequence-Specific "Gene Signatures" can be Obtained by PCR with Single Specific Primers at Low Stringency
- Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
- Sorting Functions of the Individual Cytoplasmic Domains of the G Protein-Coupled Vasopressin V2 Receptor in Madin Darby Canine Kidney Epithelial Cells
- Structure and Chromosomal Localization of the Human Antidiuretic Hormone Receptor Gene
- Switch from an Aquaporin to a Glycerol Channel by Two Amino Acids Substitution
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Molecular Basis of Renal Tubular Transport Disorders
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus
- Urinary Excretion of Aquaporin-2 in Humans: A Potential Marker of Collecting Duct Responsiveness to Vasopressin
- Urinary Excretion of Aquaporin-2 in Term and Preterm Infants
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Water Channels and Urea Transporters
- Water Transport Across Mammalian Cell Membranes
- [Hereditary Nephrogenic Diabetes Insipidus] (French)
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 12 Article bodies
Used in 12 Article bodies
- A Novel Polymorphism in the Coding Region of the Vasopressin Type 2 Receptor Gene
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Indomethacin
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus in North America. The Hopewell Hypothesis
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients
Used in 50 Article translations
Used in 50 Article translations
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Variant of Nephrogenic Diabetes Insipidus: V2 Receptor Abnormality Restricted to the Kidney
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Assignment of the Human Gene for the Water Channel of Renal Collecting Duct Aquaporin 2 (AQP2) to Chromosome 12 Region q12-->q13
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Cloning of the Human Type-2 Vasopressin Receptor Gene
- Cloning, Characterization, and Chromosomal Mapping of Human Aquaporin of Collecting Duct
- Comparative Mapping on the Mouse and Human X Chromosomes of a Human cDNA Clone Encoding the Vasopressin Renal-Type Receptor (AVP2R)
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Effect of an Acute Oral Ibuprofen Intake on Urinary Aquaporin-2 Excretion in Healthy Humans
- Expression Cloning of the Human V2 Vasopressin Receptor
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Hereditary Vasopressin Resistance in Man and Mouse
- Homer Smith: His Contribution to the Practice of Nephrology
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Isolation of Human aquaporin-CD Gene
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Mechanisms and Regulation of Water Transport in the Kidney
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Molecular Aspects of Vasopressin Receptor Function
- Molecular Mechanisms for the Regulation of Water Transport in Amphibian Epithelia by Antidiuretic Hormone
- Mutations in the Founder of the MIP Gene Family Underlie Cataract Development in the Mouse
- Nephrogenic Diabetes Insipidus in Mice Lacking All Nitric Oxide Synthase Isoforms
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Pathogenesis and Treatment of Autosomal-Dominant Nephrogenic Diabetes Insipidus Caused by an Aquaporin 2 Mutation
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Phosphorylation of the V2 Vasopressin Receptor
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Polyuria and Polydipsia. Problems Associated with Patient Evaluation
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Role of Aquaporin Water Channels in Kidney and Lung
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Ins and Outs of Aquaporin-2 Trafficking
- The Molecular Structure of the Antidiuretic Hormone Elicited Water Channel
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Vasopressin Type 2 Receptor Gene. Chromosomal Localization and Its Role in Nephrogenic Diabetes Insipidus
- Type 2 Vasopressin Receptor Gene, the Gene Responsible for Nephrogenic Diabetes Insipidus, Maps to Xq28 Close to the LICAM Gene
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- Urinary Excretion of Aquaporin-2 in Humans: A Potential Marker of Collecting Duct Responsiveness to Vasopressin
- Water Channels
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 28 Proceeding abstracts
Used in 28 Proceeding abstracts
- A proposal for the building and maintenance of an AVPR2 molecular model database
- An impaired routing of wild type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
- Clinical Phenotype and Molecular Characterization of A Mutant V2 Receptor Associated with Partial Congenital Nephrogenic Diabetes Insipidus
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Contribution of chloride channels in urine concentrating ability
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Generation of Germ Line Heterozygous Mice for Aquaporin-2 Conditional Knock-Out and Knock-In Models of NDI
- High proportion of ROMK processing defects underlying hyperprostaglandin E syndrome/antenatal Bartter syndrome
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long-range transcriptional regulation of the AVPR2 gene
- New insights in water channel physiology revealed by transgenic mouse models
- O-Glycosylation of the V2 vasopressin receptor
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Production and purification of Aquaporin-2 and Vasopressin 2 Receptor: towards elucidation of the structure
- Progress in the function and structure of aquaporin-1 and aquaporin-2
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Targeting of the V2 Vasopressin Receptor Gene in Mice
- The Medical Geneticist's Perspective on NDI Research
- The Ontogeny and Regulation of AQP2 Gene Expression in the Ovine Fetal Kidney
- Toward a mouse model of human non-X-linked NDI
- Toward gene therapy for nephrogenic diabetes insipidus
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor function studied in mice and yeast
- V2 vasopressin receptor-deficient mouse model: Pathophysiological changes and therapeutical implications
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 10 Proceeding translations
Used in 10 Proceeding translations
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Generation of Germ Line Heterozygous Mice for Aquaporin-2 Conditional Knock-Out and Knock-In Models of NDI
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Targeting of the V2 Vasopressin Receptor Gene in Mice
- The Ontogeny and Regulation of AQP2 Gene Expression in the Ovine Fetal Kidney
- Toward a mouse model of human non-X-linked NDI
- Toward gene therapy for nephrogenic diabetes insipidus
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor function studied in mice and yeast
Used in 105 Term definitions
Used in 105 Term definitions
- AQP channels
- AQP-2 water channels
- AQP2 protein
- Am allotypes
- Anthropoidea
- CTL
- Candida
- Clostridium difficile
- Fahrenheit scale
- HLA complex
- Haemophilus influenzae
- Kveim test
- Lyon hypothesis
- Mycobacterium avium-intracellulare
- Mycobacterium leprae
- Mycobacterium tuberculosis
- NDI Abstract of Article: 510
- NDI Abstract of Article: 538
- NDI Abstract of Article: 539
- Pneumovirus
- T lymphocytes
- antilymphocyte serum
- aquaporin
- aquaporin (AQP) water channels
- aquaporin membrane water channels
- aquaporin water channels
- aquaporins
- back
- blank
- blood group
- body water
- brushite
- cadaver
- carpus
- caudal
- chorion
- chromosome 21
- contactant
- copulation
- cowpox
- cytotoxic T lymphocytes
- dorsal
- dorsum
- drive
- electronic-imaging
- embryonic disc
- erythrocytes
- estrus
- factor
- fetus
- fibrinogen
- gastrula
- glandula pinealis
- hV(2)R
- helper cells
- heterogametic
- hippuric acid
- hominids
- horizon
- human
- human being
- human leukocyte antigens
- humankind
- immunoglobulin chains
- incarnation
- infant
- insulin
- lens
- leucine
- linguistic
- lysine
- male-heterogametic
- male-heterogametic species
- mammary gland
- menopause
- menstruation
- model system
- natural
- newborn
- ovum
- pedigree
- pelvic limb
- placenta
- primate
- primates
- psychoanalysis
- psychology
- rat
- reproductive period
- sewage
- social
- social sciences
- streptococcus and Streptococcus
- suppressor cells
- thoracic limb
- total body water
- tryptophan
- uterus
- valine
- ventral
- ventrally
- visible light
- whole blood
- wild
- yolk sac



