Molecular Endocrinology

6 Articles

• An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
• An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
• Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
• Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
• Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
• Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity