iodine

The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.

DEFINITION:

iodine
1. A halogen element of a peculiar odor and acrid taste; symbol, I; atomic number, 53; atomic weight, 126.904. It is a nonmetallic element, occurring in heavy, grayish black plates or granules. Iodine is essential in nutrition, being especially necessary for the synthesis of thyroid hormones (thyroxine and triiodothyronine), which regulate the metabolic rate in all cells.

2. [USP] A preparation of iodine used as a topical anti-infective. Iodine, usually in the form of iodides, is used in the treatment of hyperthyroidism.


iodine 123 - a radioactive isotope of iodine, atomic mass 123, having a half-life of 13.2 hours; it decays by electron capture, emitting gamma rays (0.159 MeV) and x-rays. It is used as a tracer in diagnostic imaging and as a radiation source in radiation therapy.


iodine 125 - A radioisotope of iodine, atomic mass 125, having a half-life of 60.14 days and emitting gamma rays (0.035 MeV); used as a radioactive tracer, particularly as a label in radioimmunoassays and other in vitro tests, and also for thyroid imaging.


iodine 131 - A radioactive isotope of iodine, atomic mass 131, having a half-life of 8.04 days; it emits beta particles (0.607, 0.81, 0.336 MeV) and gamma rays (0.080, 0.284, 0.364, 0.637, 0.723 MeV) and is used as a tracer in diagnostic imaging and as a radiation source in radiation therapy.