mediated
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- mediated
-
Accomplished by the aid of an intervening medium.
Used in 58 Article abstracts
Used in 58 Article abstracts
- A New Series of Photoactivatable and Iodinatable Linear Vasopressin Antagonists
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Aquaporin-2: COOH Terminus is Necessary But Not Sufficient for Routing to the Apical Membrane
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Chlorpropamide Upregulates Antidiuretic Hormone Receptors and Unmasks Constitutive Receptor Signaling
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Constitutive Arrestin-Mediated Desensitization of a Human Vasopressin Receptor Mutant Associated with Nephrogenic Diabetes Insipidus
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Cyclooxygenase-2 Inhibitor Preserves Medullary Aquaporin-2 Expression and Prevents Polyuria After Ureteral Obstruction
- Decreased Vasopressin-Mediated Renal Water Reabsorption in Rats with Compensated Liver Cirrhosis
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Do Aquaporins Have a Role in Nocturnal Enuresis?
- Downregulation of Aquaporin-2 and -3 in Aging Kidney is Independent of V2 Vasopressin Receptor
- Downregulation of Renal Vasopressin V2 Receptor and Aquaporin-2 Expression Parallels Age-Associated Defects in Urine Concentration
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- Effects of Dietary Fat, NaCl, and Fructose on Renal Sodium and Water Transporter Abundances and Systemic Blood Pressure
- Endocytosis in Renal Proximal Tubules. Experimental Electron Microscopical Studies of Protein Absorption and Membrane Traffic in Isolated, In Vitro Perfused Proximal Tubules
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Loss of Calcineurin Aα Results in Altered Trafficking of AQP2 and in Nephrogenic Diabetes Insipidus
- Molecular Aspects of Vasopressin Receptor Function
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Nonmuscle Myosin II and Myosin Light Chain Kinase are Downstream Targets for Vasopressin Signaling in the Renal Collecting Duct
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Osmoregulation and Baroregulation of Plasma Vasopressin in Essential Hypertension
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Pathophysiology of Renal Fluid Retention
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Rat Kidney Papilla Contains Abundant Synaptobrevin Protein that Participates in the Fusion of Antidiuretic Hormone-regulated Water Channel-containing Endosomes In Vitro
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Relief of Nocturnal Enuresis by Desmopressin is Kidney and Vasopressin Type 2 Receptor Independent
- Rescue of a Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutant by Cell-Penetrating Peptides
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Role of the Cytoplasmic Termini in the Sorting and Shuttling of the Aquaporin-2 Water Channel
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- The Ins and Outs of Aquaporin-2 Trafficking
- Therapeutic Potential of Vasopressin Receptor Antagonists
- Upregulation of Aquaporin 2 Water Channel Expression in Pregnant Rats
- Urinary Concentrating Function in Mice Lacking EP3 Receptors for Prostaglandin E2
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin Activates Collecting Duct Urea Transporters and Water Channels by Distinct Physical Processes
- Vasopressin Increases Urinary Albumin Excretion in Rats and Humans: Involvement of V2 Receptors and the Renin-Angiotensin System
- Vasopressin and Oxytocin Receptors
- Vasopressin receptors.
- Vasopressin- and cAMP-Induced Changes in Ultrastructure of Isolated Perfused Inner Medullary Collecting Ducts
Used in 7 Article bodies
Used in 7 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Indomethacin
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients
Used in 24 Article translations
Used in 24 Article translations
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Foscarnet Alters Antidiuretic Hormone-Mediated Transport
- From Vasopressin Receptor to Water Channel: Intracellular Traffic, Constraint and By-pass
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Kidney Damage in Long-Term Lithium Patients: A Cross-Sectional Study of Patients with 15 Years or More on Lithium
- Kinetics of Urea and Water Permeability Activation by Vasopressin in Rat Terminal IMCD
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Indomethacin
- Mechanism of Vasopressin Action in the Renal Collecting Duct
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Nephrogenic Diabetes Insipidus: Causes Revealed
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Pathophysiology of Aquaporin-2 in Water Balance Disorders
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Regulation of Collecting Duct Water Permeability Independent of cAMP-Mediated AVP Response
- Vasopressin Effects on Urea and H20 Transport in Inner Medullary Collecting Duct Subsegments
Used in 22 Proceeding abstracts
Used in 22 Proceeding abstracts
- A pharmacological chaperone acting at the V2-vasopressin receptor offers a treatment for Nephrogenic Diabetes Insipidus
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Correction of age-related polyuria by dDAVP: Molecular involvement of aquaporins and urea transporters
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Modulation of vasopressin-dependent AQP2 expression in cultured mpkCCDc14 collecting duct principal cells by aldosterone, insulin, and hypertonicity
- Naturally occurring and in vitro mutations defining the role of the NPXXY motif in the vasopressin V2 receptor
- Osmolality and solute composition regulate aquaporin-2 expression in primary cultured renal principal cells
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- Production and purification of Aquaporin-2 and Vasopressin 2 Receptor: towards elucidation of the structure
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Recycling of the V2 Vasopressin Receptor
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- V2 vasopressin receptor-arrestin interactions
- V2 vasopressin receptor-deficient mouse model: Pathophysiological changes and therapeutical implications
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
Used in 24 Term definitions
Used in 24 Term definitions
- 1-desamino-8-D-arginine vasopressin
- antibody-mediated hypersensitivity
- autoantigen
- autoimmunity
- cell-mediated immunity
- cellular immunity
- chemical stimuli
- clathrin
- color vision
- delayed hypersensitivity
- delayed hypersensitivity reaction
- delayed-type hypersensitivity
- humoral immunity
- immediate (type I) hypersensitivity
- immediate hypersensitivity
- immediate hypersensitivity reaction
- immunocompetence
- immunologic tolerance
- macrophage
- mediator
- type I (immediate) hypersensitivity
- type IV hypersensitivity
- vitamin B12
- vitamin B12
