mole

The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.

DEFINITION:

mole
1. That amount of substance (in a system) that contains as many elementary entities (e.g., atoms, ions, molecules, or radicals) as there are carbon atoms in 12 grams of carbon 12 (12C); thus one mole equals 6.023 X 1023 (Avogadro's number) elementary entities. Formerly, the connotation of mole was gram molecular weight and the two terms were sometimes used synonymously. Abbreviated mol.
2. A nevocytic nevus; the term is also used to designate a pigmented fleshy growth, and is applied loosely to any blemish of the skin.
3. A fleshy mass or tumor formed in the uterus by the degeneration or abnormal development of a fertilized ovum.