activity
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- activity
-
1. The state of being active; the ability to produce some effect; the extent of some function or action.
2. A thermodynamic quantity that represents the effective concentration of a solute in a nonideal solution; if concentrations are replaced by activities, the equations for equilibrium constants, electrode potentials, osmotic pressure, boiling point elevation, freezing point depression, and vapor pressures of volatile solutes are converted from approximations that hold only for dilute solutions to exact equations that hold for all concentrations. The activity is equal to the product of the concentration and the activity coefficient, a dimensionless number measuring deviation from nonideality. Symbol a.
3. For radioactivity, the number of disintegrations per unit time of a radioactive material, measured in curies or becquerels. Symbol A.
4. In electroencephalography and electromyography, the presence of recordable electrical energy in a muscle or nerve.
5. Optical activity.
Used in 56 Article abstracts
Used in 56 Article abstracts
- A Role for K268 in V2R Folding
- ADH Resistance of LLC-pk1 Cells Caused by Overexpression of cAMP-Phosphodiesterase Type-IV
- AVPR2 Variants and V2 Vasopressin Receptor Function in Nephrogenic Diabetes Insipidus
- Aggravation of Subclinical Diabetes Insipidus During Pregnancy
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Appropriate Polarization Following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-Linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
- Bradykinin Signaling Counteracts cAMP-elicited aquaporin 2 translocation in renal cells
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Characterization of SR 121463A, A Highly Potent and Selective, Orally Active Vasopressin V2 Receptor Antagonist
- Chlorpropamide Upregulates Antidiuretic Hormone Receptors and Unmasks Constitutive Receptor Signaling
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Fibrinolytic Responses to 1-desamino-8-D-arginine-vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- First Intracellular Loop of the Human Cholecystokinin-A Receptor is Essential for Cyclic AMP Signaling in Transfected HEK-293 Cells
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Heat Shock Protein 70 Interacts with Aquaporin-2 (AQP2) and Regulates Its Trafficking
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Hereditary Vasopressin Resistance in Man and Mouse
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Induction of Intramembranous Particle Clusters in Mice with Nephrogenic Diabetes Insipidus
- Long Term Regulation of Aquaporin-2 Expression in Vasopressin-responsive Renal Collecting Duct Principal Cells
- Loss of Calcineurin Aα Results in Altered Trafficking of AQP2 and in Nephrogenic Diabetes Insipidus
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Molecular Neurobiology and Pharmacology of the Vasopressin/Oxytocin Receptor Family
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Palmitoylation of the V2 Vasopressin Receptor
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Potential Role of Increased Sympathetic Activity in Impaired Sodium and Water Excretion in Cirrhosis
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Reverse Pharmacological Effect of Loop Diuretics and Altered rBSC1 Expression in Rats with Lithium Nephropathy
- Role of cAMP-Phosphodiesterase Isozymes in Pathogenesis of Murine Nephrogenic Diabetes Insipidus
- Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
- The Apical Compartment: Trafficking Pathways, Regulators and Scaffolding Proteins
- The Proteasome is Involved in the Degradation of Different Aquaporin-2 Mutants Causing Nephrogenic Diabetes Insipidus
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Transport Defects of Rabbit Inner Medullary Collecting Duct Cells in Obstructive Nephropathy
- Truncated V2 Vasopressin Receptors as Negative Regulators of Wild-Type V2 Receptor Function
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Vasopressin Activates Collecting Duct Urea Transporters and Water Channels by Distinct Physical Processes
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
Used in 12 Article bodies
Used in 12 Article bodies
- A Novel Polymorphism in the Coding Region of the Vasopressin Type 2 Receptor Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus Following High Dose Epirubicin Chemotherapy for Metastatic Soft Tissue Sarcoma [Letter]
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Nephrogenic Diabetes Insipidus in a Patient Taking Cidofovir
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Risk Factors for Ifosfamide Nephrotoxicity in Children
- Role of Vasopressin in Abnormal Water Excretion in Cirrhotic Patients
Used in 53 Article translations
Used in 53 Article translations
- ADH Resistance of LLC-pk1 Cells Caused by Overexpression of cAMP-Phosphodiesterase Type-IV
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Biochemical Basis of Partial Nephrogenic Diabetes Insipidus Phenotypes
- Cloning of the Human Type-2 Vasopressin Receptor Gene
- Cognitive and Psychosocial Functioning of Patients with Congenital Nephrogenic Diabetes Insipidus
- Colocalization of the Gene for Nephrogenic Diabetes Insipidus (DIR) and the Vasopressin Type 2 Receptor Gene (AVPR2) in the Xq28 Region
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Constitutive Nitric Oxide Synthase in Hypothalami of Normal and Hereditary Diabetes Insipidus Rats and Mice: Role of Nitric Oxide in Osmotic Regulation and its Mechanism
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Expression Cloning of the Human V2 Vasopressin Receptor
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Fibrinolytic Responses to 1-desamino-8-D-arginine-vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- High Activity of Low-Michaelis-Menten Constant 3',5'-Cyclic Adenosine Monophosphate-Phosphodiesterase Isozymes in Renal Inner Medulla of Mice With Hereditary Nephrogenic Diabetes Insipidus
- Hypokalemic Nephropathy and Nephrogenic Diabetes Insipidus Due to Excessive Consumption of a Soft Drink
- Indomethacin in the Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus
- Induction of Intramembranous Particle Clusters in Mice with Nephrogenic Diabetes Insipidus
- Insulin Potentiates AVP-induced AQP2 Expression in Cultured Renal Collecting Duct Principal Cells
- Is Testing with dDAVP Useful in Detecting Carriers of the Nephrogenic Diabetes Insipidus Gene?
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Meniere's Disease in Congenital Nephrogenic Diabetes Insipidus: Report of Two Twins
- Molecular Analyses of the Vasopressin Type 2 Receptor and Aquaporin-2 Genes in Brazilian Kindreds with Nephrogenic Diabetes Insipidus
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus Secondary to Lithium Therapy in the Postoperative Patient: A Case Report
- Nephrogenic Diabetes Insipidus: Clinical Symptoms, Pathogenesis, Genetics and Treatment
- Nephrogenic Diabetes Insipidus: Identification of the Genetic Defect
- Pathophysiology of the Aquaporin Water Channels
- Pemetrexed-Induced Acute Renal Failure, Nephrogenic Diabetes Insipidus, and Renal Tubular Acidosis in a Patient with Non-Small Cell Lung Cancer
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Phosphorylation of the V2 Vasopressin Receptor
- Role of Inner Medullary Collecting Duct NaCl Transport in Urinary Concentration
- Role of cAMP-Phosphodiesterase Isozymes in Pathogenesis of Murine Nephrogenic Diabetes Insipidus
- Rolipram, a Phosphodiesterase Inhibitor, in the Treatment of Two Male Patients with Congenital Nephrogenic Diabetes Insipidus
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Transport Defects of Rabbit Inner Medullary Collecting Duct Cells in Obstructive Nephropathy
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin-Sensitive Adenylate Cyclase: Subunit Interactions Assessed by Target Analysis and Computer Modelling
- Water Transport Across Mammalian Cell Membranes
Used in 20 Proceeding abstracts
Used in 20 Proceeding abstracts
- Biochemical Characterization of Partial Nephrogenic Diabetes Insipidus (NDI) Phenotypes
- Clinical presentation of the polyuric and hyperprostaglandinuric salt losing tubulopathies (HPS/aBS) and the therapeutic option with COX inhibitors
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Defective urinary concentrating function in transgenic mice lacking urea transporter UT-B
- Effects of Carbenoxolone on Sodium Transporter and Aquaporin-2 Abundance in Kidney
- Identification of sequence determinants that direct different intracellular folding pathways for kidney aquaporins
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Long-range transcriptional regulation of the AVPR2 gene
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Structure of V2 vasopressin receptor oligomers: evidence for contact dimer formation
- Structure-Function Analysis of the V2 Vasopressin Receptor
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
- Urinary Concentrating Defect in Mice With Selective Deletion of Collecting-Duct Urea Transporter Isoforms, UT-A1 and UT-A3
- V2 Vasopressin Receptors in NDI: Where did they go?
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
Used in 10 Proceeding translations
Used in 10 Proceeding translations
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Biochemical Characterization of Partial Nephrogenic Diabetes Insipidus (NDI) Phenotypes
- Clinical presentation of the polyuric and hyperprostaglandinuric salt losing tubulopathies (HPS/aBS) and the therapeutic option with COX inhibitors
- Effects of Carbenoxolone on Sodium Transporter and Aquaporin-2 Abundance in Kidney
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Long-range transcriptional regulation of the AVPR2 gene
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Structure of V2 vasopressin receptor oligomers: evidence for contact dimer formation
- Structure-Function Analysis of the V2 Vasopressin Receptor
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
Used in 138 Term definitions
Used in 138 Term definitions
- A, A, A, a, a, a, a
- CTL
- G protein
- G proteins
- G-protein
- GTPase
- GTPase-activating protein
- GTPase-activating proteins
- Gs protein
- Liddle's syndrome
- Niemann-Pick disease
- V2 agonists
- action potential
- activation
- activity
- agitation
- agonist
- alkaline phosphatase
- anestrus
- angiotensin I
- anthracycline
- apex
- attitude
- autonomic nervous system
- autonomous bladder
- behavior
- behavioral
- biological processes
- biotransformation
- blank
- blocker
- blockers
- brain dead
- cAMP-dependent protein kinase
- calling
- carbon tetrachloride
- ceruloplasmin
- charged
- circumscription
- cisplatin
- cobalamin
- congenital lactose intolerance
- corticosteroid
- cortisol
- cyclooxygenase
- cyclooxygenase-2 (COX-2)
- cytotoxic T lymphocytes
- delirium
- depression
- desmopressin acetate
- disaccharidase deficiency
- doxorubicin
- elation
- electrocardiogram
- electromyography
- epigenetic
- feedback
- function
- glucocorticoid
- glycosylceramidase
- ground
- heterosexuality
- homosexuality
- hormone
- hormones
- hydrocortisone
- hyperactivity
- hypersexuality
- hypothalamus
- hypothyroidism
- iatrogenic
- idea
- inactivated
- inactivation
- industrial
- inhibitor
- inhibitors
- insulin
- integration
- intellectual
- intensified
- intensity
- intermittent
- kininase
- lactase
- lactase deficiency
- lactose intolerance
- life
- liver transplant
- low-renin hypertension
- luteinizing hormone
- lymphoblastic leukemia
- macrophage
- manic phase
- mediator
- mental processes
- mineralocorticoids
- needle electrode
- non-steroidal anti-inflammatory drug
- operator gene
- orbit
- outbreak
- pH
- pharmacokinetics
- placebo
- potentiate
- proenzyme
- proestrus
- promoter
- prosthetic group
- protein kinase C
- psychomotor
- psychomotor agitation
- recruit
- reflex
- regimen
- regulatory gene
- retinal
- sexual
- sexuality
- spectrum
- sphere
- stimulate
- stimulated
- stimulates
- stimulating
- stimulation
- stimulator
- stimulatory
- suppressor cells
- tetracyclines
- tuberculin
- unstable
- value
- virus
- vitamin B12
- vitamin B12
- waste
