site
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- site
-
A place, position, or locus.
Used in 18 Article abstracts
Used in 18 Article abstracts
- Identification of Mutations in the Arginine Vasopressin Receptor 2 Gene in Congenital Nephrogenic Diabetes Insipidus Patients
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- Aquaporin-2 Trafficking is Regulated by PDZ-domain Containing Protein SPA-1
- Atrial Natriuretic Factor Inhibits Vasopressin-Stimulated Osmotic Water Permeability in Rat Inner Medullary Collecting Duct
- Foscarnet Alters Antidiuretic Hormone-Mediated Transport
- Functional Rescue of the Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutants G185C and R202C by a Second Site Suppressor Mutation
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Identification of Agonist Binding Sites of Vasopressin and Oxytocin Receptors
- Isolation of Human aquaporin-CD Gene
- Lithium Nephrotoxicity
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones: Potential Treatment for Conformational Diseases
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Rat Renal Arcade Segment Expresses Vasopressin-regulated Water Channel and Vasopressin V2 Receptor
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Two Novel Mutations in the Vasopressin V2 Receptor Gene in Patients with Congenital Nephrogenic Diabetes Insipidus
Used in 9 Article bodies
Used in 9 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Defective Aquaporin-2 Trafficking in Nephrogenic Diabetes Insipidus and Correction by Chemical Chaperones
- Efficacy of COX-2 Inhibitors in a Case of Congenital Nephrogenic Diabetes Insipidus
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Gabapentin-Related Changes in Renal Function: Two Case Studies
- High Serum Immunoreactive Trypsin Not Caused by Cystic Fibrosis (letter)
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
Used in 47 Article translations
Used in 47 Article translations
- Amphotericin B Decreases Adenylyl Cyclase Activity and Aquaporin-2 Expression in Rat Kidney
- An Aquaporin-2 Water Channel Mutant Which Causes Autosomal Dominant Nephrogenic Diabetes Insipidus is Retained in the Golgi Complex
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- Autosomal Recessive Inheritance of Vasopressin-Resistant Diabetes Insipidus
- Brief Report: A Molecular Defect in the Vasopressin V2-Receptor Gene Causing Nephrogenic Diabetes Insipidus
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Congenital Nephrogenic Diabetes Insipidus
- Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Diabetes Insipidus (Hendy, Bichet)
- Functional Rescue of the Nephrogenic Diabetes Insipidus-Causing Vasopressin V2 Receptor Mutants G185C and R202C by a Second Site Suppressor Mutation
- Functional Water Channels Are Present in Clathrin-coated Vesicles from Bovine Kidney but Not from Brain
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Misfolding of Mutant Aquaporin-2 Water Channels in Nephrogenic Diabetes Insipidus
- Molecular Biology of Diabetes Insipidus
- Molecular Genetic Study of Congenital Nephrogenic Diabetes Insipidus and Rescue of Mutant Vasopressin V2 Receptor by Chemical Chaperones
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Mutations in the Vasopressin V2 Receptor Gene in Two Families with Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2-Receptor Gene in Three Families of Italian Descent with Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus--Prodromal Phase of Multiple Myeloma
- Nephrogenic Diabetes Insipidus: Causes Revealed
- Nephrogenic Diabetes Insipidus: Clinical Symptoms, Pathogenesis, Genetics and Treatment
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- On Hereditary Diabetes Insipidus With Special Regard to a Sex-Linked Form
- Palmitoylation of the V2 Vasopressin Receptor
- Pathophysiology of the Aquaporin Water Channels
- Pharmacologic Chaperones as a Potential Treatment for X-linked Nephrogenic Diabetes Insipidus
- Pharmacological Chaperones: Potential Treatment for Conformational Diseases
- Phosphorylation of Aquaporin-2 does not alter the Membrane Water Permeability of Rat Papillary Water Channel-containing Vesicles
- Physiology and Pathophysiology of Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Clinical Importance of the Urinary Excretion of Aquaporin-2
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin Receptors in Health and Disease
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 16 Proceeding abstracts
Used in 16 Proceeding abstracts
- Action Mechanism of Pharmacological Chaperones Acting on the V2 Vasopressin Receptor in the Treatment of Nephrogenic Diabetes Insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Congenital (present a birth) severe diabetes insipidus. Most patients have nephrogenic diabetes insipidus (NDI), but some patients have autosomal recessive central (neurogenic) diabetes insipidus
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Long-range transcriptional regulation of the AVPR2 gene
- O-Glycosylation of the V2 vasopressin receptor
- Osmolality and solute composition regulate aquaporin-2 expression in primary cultured renal principal cells
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
- Thirteen Large Deletions/Rearrangements of the AVPR2 Gene Causing X-linked Nephrogenic Diabetes Insipidus
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 13 Proceeding translations
Used in 13 Proceeding translations
- Calcineurin A-alpha knockout is a new model of nephrogenic diabetes insipidus
- Chemical Chaperones as a Novel Therapeutic Strategy for NDI
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Congenital (present a birth) severe diabetes insipidus. Most patients have nephrogenic diabetes insipidus (NDI), but some patients have autosomal recessive central (neurogenic) diabetes insipidus
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Impaired routing of AQP2 to late endosomes/lysosomes following heterotetramerization with AQP2-E258K is likely to explain dominant nephrogenic diabetes insipidus
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long-range transcriptional regulation of the AVPR2 gene
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Nephrogenic diabetes insipidus in Italian families
- O-Glycosylation of the V2 vasopressin receptor
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Role of phosphorylation in the trafficking and shuttling of the Aquaporin-2 water channel
Used in 50 Term definitions
Used in 50 Term definitions
- Fc receptors
- H1 and H1
- H2
- Kveim test
- antigen-binding site
- antigenic determinant
- arrhythmia
- autograft
- bifurcatio
- blood tests
- breast cancer
- cancer
- collagenoblasts
- cytoplasm
- dose
- down-regulates
- downregulation
- genu
- histamine1
- histamine2
- implantation
- in situ
- intersection
- lambda
- local anesthetic
- localization
- localize
- locus
- macula retinae
- medulla ossium rubra
- metastasis
- myeloid tissue
- nucleolus
- origin
- parietal cells
- passive cutaneous anaphylaxis
- porta
- primary syphilis
- promoter
- sensorium commune
- suppress
- suppressed
- suppression
- synapsing
- teichoic acid
- teichoic acids
- tetanus
- tissue
- tuberculin reaction
- umbilicus
