expressed
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- expressed
-
1. Showing a detectable effect of a gene.
2. Made known; shown.
3. Squeezed out; extracted by pressing.
Used in 103 Article abstracts
Used in 103 Article abstracts
- A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2 Receptor are Essential for Cell Surface Transport in COS.M6 Cells
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Novel Deletion Mutation in the Arginine Vasopressin Receptor 2 Gene and Skewed X Chromosome Inactivation in a Female Patient with Congenital Nephrogenic Diabetes Insipidus
- A Novel Mechanism in Recessive Nephrogenic Diabetes Insipidus: Wild-Type Aquaporin-2 Rescues the Apical Membrane Expression of Intracellularly Retained AQP2-P262L
- A Role for K268 in V2R Folding
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- AVPR2 Variants and V2 Vasopressin Receptor Function in Nephrogenic Diabetes Insipidus
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- An Impaired Routing of Wild-type Aquaporin-2 after Tetramerization with an Aquaporin-2 Mutant Explains Dominant Nephrogenic Diabetes Insipidus
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Application of Difference Gel Electrophoresis (DIGE) to the Identification of Inner Medullary Collecting Duct Proteins
- Aquaporin-2, a Vasopressin-sensitive Water Channel, and Nephrogenic Diabetes Insipidus
- Aquaporin-2: COOH Terminus is Necessary But Not Sufficient for Routing to the Apical Membrane
- Aquaporins in Complex Tissues: Distribution of Aquaporins 1-5 in Human and Rat Eye
- Aquaporins in the Kidney: From Molecules to Medicine
- Aquaporins: Roles in Renal Function and Peritoneal Dialysis
- Autosomal Recessive Nephrogenic Diabetes Insipidus Caused by an Aquaporin-2 Mutation
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Characterization of an Aquaporin-2 Water Channel Gene Mutation Causing Partial Nephrogenic Diabetes Insipidus in a Mexican Family: Evidence of Increased Frequency of the Mutation in the Town of Origin
- Cloning and Expression of Apical Membrane Water Channel of Rat Kidney Collecting Tubule
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Congenital Nephrogenic Diabetes Insipidus
- Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Diversity of Nephrogenic Diabetes Insipidus Mutations and Importance of Early Recognition and Treatment
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evidence for Stabilization of Aquaporin-2 Folding Mutants by N-linked Glycosylation in the Endoplasmic Reticulum
- Evidence for a Role of Protein Kinase C-a in Urine Concentration
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Expression of VAMP-2-Like Protein in Kidney Collecting Duct Intracellular Vesicles. Colocalization with Aquaporin-2 Water Channels
- Expression of Vasopressin V1a and V2 Receptor Messenger Ribonucleic Acid in the Liver and Kidney of Embryonic, Developing, and Adult Rats
- Fourfold Reduction of Water Permeability in Inner Medullary Collecting Duct of Aquaporin-4 Knockout Mice
- Functional Analysis of Aquaporin-2 Mutants Associated with Nephrogenic Diabetes Insipidus by Yeast Expression
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- Functional Studies of Twelve Mutant V2 Vasopressin Receptors Related to Nephrogenic Diabetes Insipidus: Molecular Basis of a Mild Clinical Phenotype
- Glycosylation is Important for Cell Surface Expression of the Water Channel Aquaporin-2, But is Not Essential for Tetramerization in the Endoplasmic Reticulum
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- Impaired Solute Accumulation in Inner Medulla of Clcnk1-/- Mice Kidney
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- In Vivo Role of CLC Chloride Channels in the Kidney
- Large-Scale Purification of Functional Recombinant Human Aquaporin-2
- Long Term Regulation of Aquaporin-2 Expression in Vasopressin-responsive Renal Collecting Duct Principal Cells
- Long-Term Regulation of Four Renal Aquaporins in Rats
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Mild Nephrogenic Diabetes Insipidus Caused by Foxa1 Deficiency
- Misfolded Vasopressin V2 Receptors Caused by Extracellular Point Mutations Entail Congenital Nephrogenic Diabetes Insipidus.
- Molecular Basis of V2 Vasopressin Receptor/Gs Coupling Selectivity
- Molecular Mechanisms of Urea Transport
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus in Mice Lacking Aquaporin-3 Water Channels
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Nephrogenic diabetes insipidus.
- Osmoregulation and Baroregulation of Plasma Vasopressin in Essential Hypertension
- Pathogenesis of Nephrogenic Diabetes Insipidus by Aquaporin-2 C-Terminus Mutations
- Phosphorylation of the V2 Vasopressin Receptor
- Physiological Importance of Aquaporin Water Channels
- Physiological relevance of aquaporins: luxury or necessity?
- Physiology and Pathophysiology of Renal Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Proteomic Analysis of Long-Term Vasopressin Action in Inner Medullary Collecting Duct of Brattleboro Rat
- Rat Renal Arcade Segment Expresses Vasopressin-regulated Water Channel and Vasopressin V2 Receptor
- Recent Advances in Water Transport
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Renal Aquaporins
- Renal Water Channel Expression in Newborns: Measurement of Urinary Excretion of Aquaporin-2
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Routing of the aquaporin-2 water channel in health and disease.
- Segment Specific ENaC Downregulation in Kidney of Rats with Lithium-Induced NDI
- Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
- Sorting Functions of the Individual Cytoplasmic Domains of the G Protein-Coupled Vasopressin V2 Receptor in Madin Darby Canine Kidney Epithelial Cells
- Structure and Function of Aquaporin Water Channels
- Structure and Function of Kidney Water Channels
- The 17 kDa Band Identified by Multiple Anti-Aquaporin 2 Antisera in Rat Kidney Medulla is a Histone
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Aquaporins. A Family of Water Channel Proteins
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Effect of Eight V2 Vasopressin Receptor Mutations on Stimulation of Adenylyl Cyclase and Binding to Vasopressin
- The Interaction of Blood Osmolality and Blood Volume in Regulating Plasma Vasopressin in Man
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Topology of Eukaryotic Multispanning Transmembrane Proteins: Use of LacZ Fusions for the Localization of Cytoplasmic Domains in COS.M6 Cells
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Urinary Concentrating Function in Mice Lacking EP3 Receptors for Prostaglandin E2
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- Urinary Excretion of Aquaporin-2 in Term and Preterm Infants
- Variant Amino Acids in the Extracellular Loops of Murine and Human Vasopressin V2 Receptors Account for Differences in Cell Surface Expression and Ligand Affinity
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Water Transport Across Mammalian Cell Membranes
- [Expression of Aquaporin in Rats' Endolymphatic Sac and Kidney and the Effect of Anti-Diuretic Hormone on the Expression of Aquaporin]
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 8 Article bodies
Used in 8 Article bodies
- Analysis of Vasopressin Receptor Type II (V2R) Gene in Three Japanese Pedigrees with Congenital Nephrogenic Diabetes Insipidus: Identification of a Family with Complete Deletion of the V2R Gene
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Nephrogenic Diabetes Insipidus in North America. The Hopewell Hypothesis
- Risk Factors for Ifosfamide Nephrotoxicity in Children
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 68 Article translations
Used in 68 Article translations
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Heterotrimeric G Protein of the Gi Family is Required for cAMP-triggered Trafficking of Aquaporin 2 in Kidney Epithelial Cells
- A Role for K268 in V2R Folding
- Altered Expression of COX-1, COX-2, and mPGES in Rats with Nephrogenic and Central Diabetes Insipidus
- An Aquaporin-2 Water Channel Mutant Which Causes Autosomal Dominant Nephrogenic Diabetes Insipidus is Retained in the Golgi Complex
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Aquaporin-2 Water Channel Mutations and Nephrogenic Diabetes Insipidus: New Variations on a Theme
- Aquaporins and Ion Conductance
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Autosomal Recessive Inheritance of Vasopressin-Resistant Diabetes Insipidus
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Changes of Rat Kidney AQP2 and Na,K-ATPase mRNA Expression in Lithium-Induced Nephrogenic Diabetes Insipidus
- Characterization of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus in a Polarized Cell Model
- Characterization of an Aquaporin-2 Water Channel Gene Mutation Causing Partial Nephrogenic Diabetes Insipidus in a Mexican Family: Evidence of Increased Frequency of the Mutation in the Town of Origin
- Clinical Phenotype of Nephrogenic Diabetes Insipidus in Females Heterozygous for a Vasopressin Type 2 Receptor Mutation
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Detection of Skewed X-Inactivation in Two Female Carriers of Vasopressin Type 2 Receptor Gene Mutation
- Development of Lithium-Induced Nephrogenic Diabetes Insipidus is Dissociated from Adenylyl Cyclase Activity
- Diabetes Insipidus (Robertson)
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Differential Diagnosis and Pathophysiology of Diabetes Insipidus
- Differential Diagnosis of Polyuria
- Discovery of Aquaporins: a Breakthrough in Research on Renal Water Transport
- Disease-Causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway
- Disordered Water Channel Expression and Distribution in Acquired Nephrogenic Diabetes Insipidus
- Do Aquaporins Have a Role in Nocturnal Enuresis?
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Expression Studies of Two Vasopressin V2 Receptor Gene Mutations, R202C and 804insG, in Nephrogenic Diabetes Insipidus
- Functional Analysis of Aquaporin-2 Mutants Associated with Nephrogenic Diabetes Insipidus by Yeast Expression
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Index of Suspicion. Case 2. Nephrogenic Diabetes Insipidus
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Membrane Targeting and Determination of Transmembrane Topology of the Human Vasopressin V2 Receptor
- Mild Nephrogenic Diabetes Insipidus Caused by Foxa1 Deficiency
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Molecular Aspects of Vasopressin Receptor Function
- Molecular and Cellular Defects in Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus. A V2 Vasopressin Receptor Unable to Stimulate Adenylyl Cyclase
- Palmitoylation of the V2 Vasopressin Receptor
- Pathophysiology of the Aquaporin Water Channels
- Physiology and Pathophysiology of Aquaporins
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Renal Aquaporins
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
- Structure and Chromosomal Localization of the Human Antidiuretic Hormone Receptor Gene
- Successful Treatment with Hydrochlorothiazide and Amiloride in an Infant with Congenital Nephrogenic Diabetes Insipidus
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Two Vasopressin Type 2 Receptor Gene Mutations R143P and Delta V278 in Patients with Nephrogenic Diabetes Insipidus Impair Ligand Binding of the Receptor
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- Water Channels in Cell Membranes
Used in 49 Proceeding abstracts
Used in 49 Proceeding abstracts
- Regulation of UT-A1 abundance by vasopressin and glucocorticoids
- Renal medullary gene expression in aquaporin-1 null mice
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- A defect in AQP2 phosphorylation at Ser256 in the Golgi apparatus might explain the molecular basis of the dominant form of NDI caused by the mutation E258K-AQP2
- A pharmacological chaperone acting at the V2-vasopressin receptor offers a treatment for Nephrogenic Diabetes Insipidus
- Action Mechanism of Pharmacological Chaperones Acting on the V2 Vasopressin Receptor in the Treatment of Nephrogenic Diabetes Insipidus
- An impaired routing of wild type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
- Analysis of molecular mechanisms causing V2 vasopressin receptor dysfunction in four patients with X-linked nephrogenic diabetes insipidus
- Analysis of naturally occurring and in vitro mutations of the V2 receptor gene interfering with proper splicing
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Binding properties and cAMP production study of 7 mutant V2 receptors related to cNDI
- Calcineurin A-alpha knockout is a new model of nephrogenic diabetes insipidus
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Clinical Phenotype and Molecular Characterization of A Mutant V2 Receptor Associated with Partial Congenital Nephrogenic Diabetes Insipidus
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Compartmentalization of NDI-causing vasopressin V2 receptor mutants in the early secretory pathway
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Defective urinary concentrating function in transgenic mice lacking urea transporter UT-B
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Differences between ER-retained vasopressin V2 receptor mutants in antagonist-mediated restoration of cell surface expression
- Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus: molecular basis of a mild clinical phenotype.
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Lack of AVP-induced phosphorylation of the Aquaporin-2 mutants AQP2-R254L and AQP2-R254Q explains dominant Nephrogenic Diabetes Insipidus
- Long-range transcriptional regulation of the AVPR2 gene
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- N-linked glycosylation is essential for transport of the Aquaporin-2 water channel to the plasma membrane in MDCK cells
- Nephrogenic Diabetes Insipidus Mutation Database
- Nephrogenic Diabetes Insipidus Patients in Japan
- Nephrogenic Diabetes Insipidus in mice lacking aquaporin-3 water channels
- O-Glycosylation of the V2 vasopressin receptor
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- Production and purification of Aquaporin-2 and Vasopressin 2 Receptor: towards elucidation of the structure
- Proteomic Studies of Vasopressin Action in the Collecting Duct
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Quality control of nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutants in the ER and in the ER/Golgi intermediate compartment
- Recycling of the V2 Vasopressin Receptor
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Structure-Function Analysis of the V2 Vasopressin Receptor
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- The Medical Geneticist's Perspective on NDI Research
- The stoichiometry of phosphorylated and non-phosphorylated monomers in an aquaporin-2 tetramer determines its subcellular localization
- Toward gene therapy for nephrogenic diabetes insipidus
- V2 Vasopressin Receptors in NDI: Where did they go?
- V2 vasopressin receptor function studied in mice and yeast
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 20 Proceeding translations
Used in 20 Proceeding translations
- Renal medullary gene expression in aquaporin-1 null mice
- Altered expression pattern of solute transporters in inner medulla of AQP1 (-/-) and CLC-nK1 (-/-) mice
- Analysis of naturally occurring and in vitro mutations of the V2 receptor gene interfering with proper splicing
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Functional investigations of the vasopressin regulated antidiuretic machinery in single inner medullary collecting duct (IMCD) cells
- Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus: molecular basis of a mild clinical phenotype.
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Naturally occurring and in vitro mutations defining the role of the NPXXY motif in the vasopressin V2 receptor
- Nephrogenic Diabetes Insipidus Patients in Japan
- Obstructive nephropathy -- a common acquired condition of nephrogenic diabetes insipidus
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- V2 Vasopressin Receptors in NDI: Where did they go?
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor function studied in mice and yeast
- Variations in clinical phenotype associated with different mutations of the V2 receptor gene in X-linked recessive congenital nephrogenic DI (xCNDI)
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
Used in 37 Term definitions
Used in 37 Term definitions
- NDI Abstract of Article: 539
- X-linked gene
- absorbed dose
- affinity
- applause
- characteristic
- conductivity
- conversion
- dissociation constant
- dominant gene
- down-regulates
- downregulation
- electrical resistance
- explicit
- gene
- genes
- gradient
- kinetics
- logarithm
- normalization
- normalizing
- numerical
- pH
- percentage
- ratio
- ratios
- relative
- resistance
- resistant
- resolution
- specific absorptivity
- square
- strain
- tuberculin
- urinary osmolality
- urine osmolality
- vague
