expression
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- expression
-
1. The aspect or appearance of the face (or surface of a cell) as determined by the physical or emotional state.
2. The act of squeezing or evacuating by pressure; a term used in pharmacy, surgery, and obstetrics.
3. The detectable effect of a gene.
4. A representation of value, relation, or the like (e.g., ratio).
Used in 139 Article abstracts
Used in 139 Article abstracts
- A Fully Active Nonglycosylated V2 Vasopressin Receptor
- A Novel Mechanism in Recessive Nephrogenic Diabetes Insipidus: Wild-Type Aquaporin-2 Rescues the Apical Membrane Expression of Intracellularly Retained AQP2-P262L
- A Role for K268 in V2R Folding
- AQP3, p-AQP2, and AQP2 Expression is Reduced in Polyuric Rats With Hypercalcemia: Prevention by cAMP-PDE Inhibitors
- Acute Effects of Vasopressin V2-Receptor Antagonist on Kidney AQP2 Expression and Subcellular Distribution
- Altered Expression of COX-1, COX-2, and mPGES in Rats with Nephrogenic and Central Diabetes Insipidus
- Altered Expression of Major Renal Na Transporters in Rats with Unilateral Ureteral Obstruction
- Altered Expression of Renal AQPs and Na+ Transporters in Rats with Lithium-Induced NDI
- Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus
- Amphotericin B Decreases Adenylyl Cyclase Activity and Aquaporin-2 Expression in Rat Kidney
- An Aquaporin-2 Water Channel Mutant Which Causes Autosomal Dominant Nephrogenic Diabetes Insipidus is Retained in the Golgi Complex
- An Extracellular Congenital Nephrogenic Diabetes Insipidus Mutation of the Vasopressin Receptor Reduces Cell Surface Expression, Affinity for Ligand, and Coupling to the Gs/adenylyl Cyclase System
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Co-transporter, and Epithelial Sodium Channel
- Application of Difference Gel Electrophoresis (DIGE) to the Identification of Inner Medullary Collecting Duct Proteins
- Aquaporin Expression in Normal Human Kidney and in Renal Disease
- Aquaporin-2 Expression in Primary Cultured Rat Inner Medullary Collecting Duct Cells
- Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
- Aquaporin-2: COOH Terminus is Necessary But Not Sufficient for Routing to the Apical Membrane
- Aquaporins in the Kidney: From Molecules to Medicine
- Aquaporins: Roles in Renal Function and Peritoneal Dialysis
- Association of Calnexin With Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus
- Attenuation of Renal Vasopressin V2 Receptor Upregulation by Bosentan, an ETA/ETB Receptor Antagonist
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Cell-Biologic and Functional Analyses of Five New Aquaporin-2 Missense Mutations that Cause Recessive Nephrogenic Diabetes Insipidus
- Cellular Distribution of the Aquaporins: A Family of Water Channel Proteins
- Changes in Cellular Composition of Kidney Collecting Duct Cells in Rats with Lithium-Induced NDI
- Characterization of an Aquaporin-2 Water Channel Gene Mutation Causing Partial Nephrogenic Diabetes Insipidus in a Mexican Family: Evidence of Increased Frequency of the Mutation in the Town of Origin
- Cloning and Characterization of a Vasopressin V2 Receptor and Possible Link to Nephrogenic Diabetes Insipidus
- Cloning and Expression of Apical Membrane Water Channel of Rat Kidney Collecting Tubule
- Cloning of an Aquaporin Homologue Present in Water Channel Containing Endosomes of Toad Urinary Bladder
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Congestive Heart Failure in Rats is Associated with Increased Expression and Targeting of Aquaporin-2 Water Channel in Collecting Duct
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Decreased Vasopressin-Mediated Renal Water Reabsorption in Rats with Compensated Liver Cirrhosis
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Development of Urinary Concentrating Capacity: Role of Aquaporin-2
- Development of Water Transport in the Collecting Duct
- Disease-Causing V2 Vasopressin Receptors are Retained in Different Compartments of the Early Secretory Pathway
- Disordered Water Channel Expression and Distribution in Acquired Nephrogenic Diabetes Insipidus
- Downregulation of AQP1, -2, and -3 After Ureteral Obstruction is Associated With a Long-Term Urine-Concentrating Defect
- Downregulation of Aquaporin-2 Parallels Changes in Renal Water Excretion in Unilateral Ureteral Obstruction
- Downregulation of Aquaporin-2 and -3 in Aging Kidney is Independent of V2 Vasopressin Receptor
- Downregulation of Renal Aquaporins in Response to Unilateral Ureteral Obstruction
- Downregulation of Renal Vasopressin V2 Receptor and Aquaporin-2 Expression Parallels Age-Associated Defects in Urine Concentration
- Dual Influence of Aldosterone on AQP2 Expression in Cultured Renal Collecting Duct Principal Cells
- Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct
- Escape from Vasopressin-Induced Antidiuresis: Role of Vasopressin Resistance of the Collecting Duct
- Evidence for a Role of Protein Kinase C-a in Urine Concentration
- Expression of Renal Aquaporins 1, 2, and 3 in a Rat Model of Cisplatin-Induced Polyuria
- Expression of Vasopressin V1a and V2 Receptor Messenger Ribonucleic Acid in the Liver and Kidney of Embryonic, Developing, and Adult Rats
- Fourfold Reduction of Water Permeability in Inner Medullary Collecting Duct of Aquaporin-4 Knockout Mice
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Generation and Phenotype of Mice Harboring a Nonsense Mutation in the V2 Vasopressin Receptor Gene
- Genetic Restoration of Aldose Reductase to the Collecting Tubules Restores Maturation of the Urine Concentrating Mechanism
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Hypokalemia-Induced Downregulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla and Cortex
- Identification and Characterization of Aquaporin-2 Water Channel Mutations Causing Nephrogenic Diabetes Insipidus with Partial Vasopressin Response
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Importance of Aquaporin-2 Expression Levels in Genotype -Phenotype Studies in Nephrogenic Diabetes Insipidus
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Isolation of Human aquaporin-CD Gene
- Large-Scale Purification of Functional Recombinant Human Aquaporin-2
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Long-Term Regulation of Four Renal Aquaporins in Rats
- Long-Term Regulation of Urinary Concentrating Capacity
- Long-term Regulation of Aquaporins in the Kidney
- Loss of Calcineurin Aα Results in Altered Trafficking of AQP2 and in Nephrogenic Diabetes Insipidus
- Mechanism of Antidiuresis Caused by Bendroflumethiazide in Conscious Rats with Diabetes Insipidus
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Mild Nephrogenic Diabetes Insipidus Caused by Foxa1 Deficiency
- Misfolded Vasopressin V2 Receptors Caused by Extracellular Point Mutations Entail Congenital Nephrogenic Diabetes Insipidus.
- Molecular Aspects of Vasopressin Receptor Function
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Genetic Study of Congenital Nephrogenic Diabetes Insipidus and Rescue of Mutant Vasopressin V2 Receptor by Chemical Chaperones
- Molecular Neurobiology and Pharmacology of the Vasopressin/Oxytocin Receptor Family
- Molecular and Cellular Defects in Nephrogenic Diabetes Insipidus (Knoers, Deen)
- Mutations in the Vasopressin V2 Receptor Gene in Families with Nephrogenic Diabetes Insipidus and Functional Expression of the Q-2 Mutant
- Nephrogenic Diabetes Insipidus in Mice Lacking All Nitric Oxide Synthase Isoforms
- Neurogenic Disorders of Osmoregulation
- New Mutations in the AQP2 Gene in Nephrogenic Diabetes Insipidus Resulting in Functional but Misrouted Water Channels
- Novel Down-Regulatory Mechanism of the Surface Expression of Vasopressin V2 Receptor by an Alternative Splice Receptor Variant
- Novel Mutations in Aquaporin-2 Gene in Female Siblings with Nephrogenic Diabetes Insipidus: Evidence of Disrupted Water Channel Function
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Palmitoylation of the V2 Vasopressin Receptor
- Pathophysiology of Renal Fluid Retention
- Patients with Autosomal Nephrogenic Diabetes Insipidus Homozygous for Mutations in the Aquaporin 2 Water-Channel Gene
- Pharmacological Chaperones in Nephrogenic Diabetes Insipidus: Possibilities for Clinical Application
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Physiological Importance of Aquaporin Water Channels
- Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Proteomic Analysis of Long-Term Vasopressin Action in Inner Medullary Collecting Duct of Brattleboro Rat
- Rat Renal Arcade Segment Expresses Vasopressin-regulated Water Channel and Vasopressin V2 Receptor
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Redistribution of Aquaporin-2 Water Channels Induced by Vasopressin in Rat Kidney Inner Medullary Collecting Duct
- Regulation of Aquaporin-2 Trafficking by Vasopressin in the Renal Collecting Duct
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Renal Expression of Sodium Transporters and Aquaporin-2 in Hypothyroid Rats
- Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
- Reverse Pharmacological Effect of Loop Diuretics and Altered rBSC1 Expression in Rats with Lithium Nephropathy
- Rho Inhibits cAMP-Induced Translocation of Aquaporin-2 into the Apical Membrane of Renal Cells
- Role of Renal Aquaporins in Escape from Vasopressin-induced Antidiuresis in Rat
- Routing of the aquaporin-2 water channel in health and disease.
- Structure and Chromosomal Localization of the Human Antidiuretic Hormone Receptor Gene
- The Aquaporins. A Family of Water Channel Proteins
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- The Perinatal Expression of Aquaporin-2 and Aquaporin-3 in Developing Kidney
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Treating lithium-induced nephrogenic diabetes insipidus with a COX-2 inhibitor improves polyuria via upregulation of AQP2 and NKCC2.
- Two Novel Aquaporin-2 Mutations Responsible for Congenital Nephrogenic Diabetes Insipidus in Chinese Families
- Upregulation of Aquaporin 2 Water Channel Expression in Pregnant Rats
- Upregulation of Collecting Duct Aquaporin-2 by Metabolic Acidosis: Role of Vasopressin
- Upregulation of Urea Transporter UT-A2 and Water Channels AQP2 and AQP3 in Mice Lacking Urea Transporter UT-B
- Urinary Content of Aquaporin 1 and 2 in Nephrogenic Diabetes Insipidus
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin Increases Water Permeability of Kidney Collecting Duct by Inducing Translocation of Aquaporin-CD Water Channels to Plasma Membrane
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Vasopressin and Oxytocin Receptors
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Water Channels Encoded by Mutant Aquaporin-2 Genes in Nephrogenic Diabetes Insipidus are Impaired in Their Cellular Routing
- Water Channels and Urea Transporters
- Water Transport Across Mammalian Cell Membranes
- [Expression of Aquaporin in Rats' Endolymphatic Sac and Kidney and the Effect of Anti-Diuretic Hormone on the Expression of Aquaporin]
- cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
Used in 12 Article bodies
Used in 12 Article bodies
- Hereditary Vasopressin Resistance in Man and Mouse
- Hyperosmolar Coma and Lithium-induced Diabetes Insipidus
- Importance of the Mercury-Sensitive Cysteine on Function and Routing of AQP1 and AQP2 in Oocytes
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Index of Suspicion. Case 2. Nephrogenic Diabetes Insipidus
- Molecular Analysis of X-Linked Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus--Prodromal Phase of Multiple Myeloma
- Nephrogenic Diabetes Insipidus: A Cause of Severe Nonobstructive Urinary Tract Dilatation
- Notes on Some Cases of Diabetes Insipidus with Marked Family and Hereditary Tendencies
- Proposed Cause of Marked Vasopressin Resistance in a Female with an X-Linked Recessive V2 Receptor Abnormality
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 45 Article translations
Used in 45 Article translations
- A Role for K268 in V2R Folding
- Angiotensin II Upregulates the Expression of Vasopressin V2 mRNA in the Inner Medullary Collecting Duct of the Rat
- Bilateral Ureteral Obstruction Downregulates Expression of Vasopressin-Sensitive AQP-2 Water Channel in Rat Kidney
- Binding-, Intracellular Transport-, and Biosynthesis-Defective Mutants of Vasopressin Type 2 Receptor in Patients with X-Linked Nephrogenic Diabetes Insipidus
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Clinical Phenotype of Nephrogenic Diabetes Insipidus in Females Heterozygous for a Vasopressin Type 2 Receptor Mutation
- Colocalization of the Gene for Nephrogenic Diabetes Insipidus (DIR) and the Vasopressin Type 2 Receptor Gene (AVPR2) in the Xq28 Region
- Concentrating Defect in Experimental Nephrotic Syndrome: Altered Expression of Aquaporins and Thick Ascending Limb Na+ Transporters
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Dehydration Reverses Vasopressin Antagonist-Induced Diuresis and Aquaporin-2 Downregulation in Rats
- Derivatives of Somatic Cell Hybrids Which Carry the Human Gene Locus for Nephrogenic Diabetes Insipidus (NDI) Express Functional Vasopressin Renal V2-type Receptors
- Detection of Skewed X-Inactivation in Two Female Carriers of Vasopressin Type 2 Receptor Gene Mutation
- Disordered Water Channel Expression and Distribution in Acquired Nephrogenic Diabetes Insipidus
- Do Aquaporins Have a Role in Nocturnal Enuresis?
- Fourfold Reduction of Water Permeability in Inner Medullary Collecting Duct of Aquaporin-4 Knockout Mice
- From Vasopressin Receptor to Water Channel: Intracellular Traffic, Constraint and By-pass
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Hereditary Vasopressin Resistance in Man and Mouse
- Hyperosmolar Coma and Lithium-induced Diabetes Insipidus
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Impaired Aquaporin and Urea Transporter Expression in Rats with Adriamycin-Induced Nephrotic Syndrome
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Inherited Diseases of the Kidney
- Intrafamilial Phenotype Variability in Nephrogenic Diabetes Insipidus
- Isolation of Human aquaporin-CD Gene
- Lithium-induced Down regulation of Aquaporin-2 Water Channel Expression in Rat Kidney Medulla
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanisms of Impaired Urinary Concentrating Ability in Adult Rats Treated Neonatally with Enalapril
- Novel Mutations in the V2 Vasopressin Receptor Gene in Two Pedigrees with Congenital Nephrogenic Diabetes Insipidus
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Pathophysiology of the Aquaporin Water Channels
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Physiology and Pathophysiology of the Aquaporin-2 Water Channel
- Polarized Expression of the Vasopressin V2 Receptor in Madin-Darby Canine Kidney Cells
- Regulation of Collecting Duct Water Channel Expression by Vasopressin in Brattleboro Rat
- Renal Aquaporins
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
- The Aquaporin Family of Water Channel Proteins in Clinical Medicine
- The Clinical Importance of the Urinary Excretion of Aquaporin-2
- The Molecular Basis of Nephrogenic Diabetes Insipidus
- V2 Vasopressin Receptor Dysfunction in Nephrogenic Diabetes Insipidus Caused By Different Molecular Mechanisms
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Water Channels in Cell Membranes
Used in 69 Proceeding abstracts
Used in 69 Proceeding abstracts
- Regulation of UT-A1 abundance by vasopressin and glucocorticoids
- Renal medullary gene expression in aquaporin-1 null mice
- Rescue of the Cell Surface Expression of Vasopressin V2 Receptor Mutants in Nephrogenic Diabetes Insipidus
- Altered expression pattern of solute transporters in inner medulla of AQP1 (-/-) and CLC-nK1 (-/-) mice
- Analysis of naturally occurring and in vitro mutations of the V2 receptor gene interfering with proper splicing
- Antidiuretic Effect of Hydrochlorothiazide in Lithium-Induced Nephrogenic Diabetes Insipidus Is Associated with Upregulation of Aquaporin-2, Na-Cl Cotransporter and Epithelial Sodium Channel
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Candesartan treatment prevents dysregulation of AQP2, BSC-1 and NaPi2 in ureteral obstruction-induced NDI
- Cell biological and functional analysis of five new Aquaporin-2 gene missense mutations in recessive Nephrogenic Diabetes Insipidus
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Clinical Data and Cell Biological Aspects of Mutations in Nephrogenic Diabetes Insipidus
- Clinical presentation of the polyuric and hyperprostaglandinuric salt losing tubulopathies (HPS/aBS) and the therapeutic option with COX inhibitors
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Consequences of tetramerization and expression levels of Aquaporin-2 in phenotype-genotype correlation studies in autosomal NDI
- Contribution of chloride channels in urine concentrating ability
- Correction of age-related polyuria by dDAVP: Molecular involvement of aquaporins and urea transporters
- Decreased Aquaporin-2 Water Channel Expression in Acquired Nephrogenic Diabetes Insipidus
- Determination of the functionality of AQP2 missense mutants in recessive NDI
- Downregulation of renal aquaporins and sodium transporters in rats with bilateral ureteral obstruction (BUO) is prevented by a-MSH treatment
- Dysregulation of genes in rats with lithium-induced NDI
- Effects of Carbenoxolone on Sodium Transporter and Aquaporin-2 Abundance in Kidney
- Expressional alteration of sodium transporter in the thick ascending limb of Henle and urinary concentration
- G15 reveals coupling of the V2 receptor to PLC that is refractory to receptor desensitization
- Gene Mutation Analysis of NDI patients in Japan
- Generation of Germ Line Heterozygous Mice for Aquaporin-2 Conditional Knock-Out and Knock-In Models of NDI
- High proportion of ROMK processing defects underlying hyperprostaglandin E syndrome/antenatal Bartter syndrome
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Long-range transcriptional regulation of the AVPR2 gene
- Long-term regulation of aquaporin-2: a possible therapeutic approach to NDI?
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Modulation of aquaporin-2 expression in primary cultured rat inner medullary collecting duct (IMCD) cells
- Modulation of vasopressin-dependent AQP2 expression in cultured mpkCCDc14 collecting duct principal cells by aldosterone, insulin, and hypertonicity
- Molecular mechanisms underlying dominant Nephrogenic Diabetes Insipidus caused by mutations in the AQP2 gene
- Naturally occurring and in vitro mutations defining the role of the NPXXY motif in the vasopressin V2 receptor
- Nephrogenic Diabetes Insipidus Mutation Database
- Nephrogenic Diabetes Insipidus Patients in Japan
- New insights in water channel physiology revealed by transgenic mouse models
- Osmolality and solute composition regulate aquaporin-2 expression in primary cultured renal principal cells
- Pharmacological Chaperones Functionally Rescue Misfolded V2-Vasopressin Receptor Mutants that Cause Nephrogenic Diabetes Insipidus: Potential Clinical Implications
- Pharmacological chaperones functionally rescue misfolded mutant V2 vasopressin receptors that cause nephrogenic diabetes insipidus
- Phenotype of aquaporin knockout mice, and AQP2 misprocessing in NDI
- Prostaglandins as Stimulants of AQP2 Expression: a Possible Future Treatment for NDI?
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Regulation of AQP2 trafficking and recycling by dopamine, PGE2 and ANP: involvement of AQP2-S256 phosphorylation
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Regulation of renal aquaporins and sodium transporters in conditions with urinary tract obstruction
- Routing and function of mutant AQP2 water channels in nephrogenic diabetes insipidus
- Structure of V2 vasopressin receptor oligomers: evidence for contact dimer formation
- Supplementation of Receptor Fragments: An approach to Functionally Rescue Mutant V2 Vasopressin Receptors
- The C-terminus of aquaporin-2 is necessary, but not sufficient, for routing of AQP2 to the apical membrane
- The Ontogeny and Regulation of AQP2 Gene Expression in the Ovine Fetal Kidney
- The novel Aquaporin-2 maturing protein 1 interacts with AQP2, inhibits its forskolin-induced translocation to the apical membrane, and reduces its expression
- Toward gene therapy for nephrogenic diabetes insipidus
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- Urinary Concentrating Defect in Mice With Selective Deletion of Collecting-Duct Urea Transporter Isoforms, UT-A1 and UT-A3
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor function studied in mice and yeast
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- V2 vasopressin receptor-arrestin interactions
- V2 vasopressin receptor-deficient mouse model: Pathophysiological changes and therapeutical implications
- Variations in clinical phenotype associated with different mutations of the V2 receptor gene in X-linked recessive congenital nephrogenic DI (xCNDI)
- Vasopressin-Independent Regulation of Aquaporin-2 Protein
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
- Wild-type aquaporin-2 rescues a novel aquaporin-2 mutant in recessive Nephrogenic Diabetes Insipidus to the apical plasma membrane
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 12 Proceeding translations
Used in 12 Proceeding translations
- Characterization of mutant vasopressin V2 receptors with a misfolded AVP binding site
- Collecting Duct Specific Gene Regulation: Creation And Use of Transgenic Mouse Models
- Comparative analysis of human and murine vasopressin V2 receptor genes and their encoded proteins reveal striking differences in their genomic structure and functional properties
- Expressional alteration of sodium transporter in the thick ascending limb of Henle and urinary concentration
- Lithium-induced Nephrogenic Diabetes Insipidus: A Cell Culture Model
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Modulation of aquaporin-2 expression in primary cultured rat inner medullary collecting duct (IMCD) cells
- Nephrogenic Diabetes Insipidus in a Palestine Sibship
- V2 Vasopressin Receptors in NDI: Where did they go?
- Vasopressin-V2-receptor dependent and independent regulation of collecting duct aquaporin-2 expression and trafficking
- Vasopressin-dependent and independent regulation of aquaporin-2 in rats with central diabetes insipidus
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 36 Term definitions
Used in 36 Term definitions
- affect
- affinity
- autosomal recessive
- autosomal recessive trait
- autosomal-recessive
- bladder compliance
- blood group
- character
- clinical phenotype
- compliance
- dilated cardiomyopathy
- dimension
- dominant
- dream
- elastance
- embodiment
- equation
- face
- facial nerve
- facies
- facioscapulohumeral dystrophy
- familiarity
- language
- parameter
- penetrance
- phenotype
- porphyria
- promoter
- quantification
- ratio
- ratios
- recessive
- steroid hormones
- transfected cells
- vague
- weak
