hormone
The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine, Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Biotechnology from A to Z, 2d Edition, William Bains, Oxford University Press, New York, New York, 2002; A Dictionary of Genetics, 6th Edition, Robert C. King and William D. Stansfield, Oxford University Press, New York, New York, 2002; Dorland's Illustrated Medical Dictionary, 29th and 30th Editions, W. B. Saunders Company, Philadelphia, 2000, 2003; Genes VII, Benjamin Lewin, Oxford University Press, New York, New York, 2000; The Gale Encyclopedia of Genetic Disorders, Volumes I and II, Stacey L. Blachford, Ed., Thomson Learning, New York, New York, 2002; The Merriam-Webster Dictionary, Merriam-Webster, Inc., Springfield, Massachusetts, 1997; Molecular Biology of the Cell, 3rd Edition, Bruce Alberts, et al., Garland Publishing, 1994; The Random House Dictionary of the English Language, Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary, 1991.
DEFINITION:
- hormone
-
A product of living cells that circulates in body fluids and produces a specific effect on the activity of cells remote from its point of origin; especially: one exerting a stimulatory effect on a cellular activity.
hypophysiotropic hormones - Hormones produced by the hypothalamus, usually releasing hormones (see below), which maintain the endocrine functions of cells of the adenohypophysis.
neurohormone - A hormone secreted by a specialized neuron into the bloodstream, the cerebrospinal fluid, or the intercellular spaces of the nervous system.
releasing hormones - Hormones elaborated in one structure that cause the release of hormones from another structure, such as those from the hypothalamus that act on the adenohypophysis. The term is applied to substances of established chemical identity, whereas substances of unknown chemical structure are called releasing factors .
Used in 28 Article abstracts
Used in 28 Article abstracts
- A New Series of Photoactivatable and Iodinatable Linear Vasopressin Antagonists
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- ADH Resistance of LLC-pk1 Cells Caused by Overexpression of cAMP-Phosphodiesterase Type-IV
- Agonist and Antagonist-Dependent Internalization of the Human Vasopressin V2 Receptor
- Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
- Association of Calnexin With Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus
- Clinical Use of Vasopressin Analogues
- Compound Deletion of the rhoGAP C1 and V2 Vasopressin Receptor Genes in a Patient with Nephrogenic Diabetes Insipidus
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Diabetes Insipidus (Robertson)
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- Identification of Agonist Binding Sites of Vasopressin and Oxytocin Receptors
- Identification of Mutations in the Arginine Vasopressin Receptor 2 Gene Causing Nephrogenic Diabetes Insipidus in Chinese Patients
- Isolation and Characterization of Specialized Regions of Toad Urinary Bladder Apical Plasma Membrane Involved in the Water Permeability Response to Antidiuretic Hormone
- Molecular Basis of V2 Vasopressin Receptor/Gs Coupling Selectivity
- Molecular Pathogenesis of Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus Presenting After Head Trauma
- Palmitoylation of the V2 Vasopressin Receptor
- Properties of the Human Arginine Vasopressin V2 Receptor after Site-Directed Mutagenesis of its Putative Palmitoylation Site
- Renal Expression of Sodium Transporters and Aquaporin-2 in Hypothyroid Rats
- Role of the Ca2+-Sensing Receptor in Divalent Mineral Ion Homeostasis
- Therapeutic Potential of Vasopressin Receptor Antagonists
- Vasopressin Increases Urinary Albumin Excretion in Rats and Humans: Involvement of V2 Receptors and the Renin-Angiotensin System
- Vasopressin Increases Water Permeability of Kidney Collecting Duct by Inducing Translocation of Aquaporin-CD Water Channels to Plasma Membrane
- Vasopressin Receptors in Health and Disease
- Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
- Vasopressin and Oxytocin Receptors Coupled to Ca2+ Mobilization in Rat Inner Medullary Collecting Duct
- [Nephrogenic Diabetes Insipidus] (Hungarian)
Used in 8 Article bodies
Used in 8 Article bodies
- Evidence that the Antidiuretic Substance in the Plasma of Children with Nephrogenic Diabetes Insipidus is Antidiuretic Hormone
- Hereditary Vasopressin Resistance in Man and Mouse
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Nephrogenic Diabetes Insipidus
- Nephrogenic Diabetes Insipidus in North America. The Hopewell Hypothesis
- Nephrogenic Diabetes Insipidus: Transmitted by Females and Appearing During Infancy in Males
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Role of Aquaporin-2 Water Channels in Urinary Concentration and Dilution Defects
Used in 117 Article translations
Used in 117 Article translations
- 1-Desamino[8-D-arginine]Vasopressin (dDAVP) Decreases Blood Pressure and Increases Pulse Rate in Normal Individuals
- A Case of a Novel Mutant Vasopressin Receptor-Dependent Nephrogenic Diabetes Insipidus With Bilateral Non-Obstructive Hydronephrosis in a Middle Aged Man
- A Low Affinity Vasopressin V2-Receptor in Inherited Nephrogenic Diabetes Insipidus
- A Low-Affinity Vasopressin V2-Receptor Gene in a Kindred with X-Linked Nephrogenic Diabetes Insipidus
- A Role for K268 in V2R Folding
- A Serine Cluster Prevents Recycling of the V2 Vasopressin Receptor
- A Variant of Nephrogenic Diabetes Insipidus: V2 Receptor Abnormality Restricted to the Kidney
- Altered Expression of COX-1, COX-2, and mPGES in Rats with Nephrogenic and Central Diabetes Insipidus
- Aminoglycoside Pretreatment Partially Restores the Function of Truncated V2 Vasopressin Receptors Found in Patients with Nephrogenic Diabetes Insipidus
- Aminoglycoside-Mediated Rescue of a Disease-Causing Nonsense Mutation in the V2 Vasopressin Receptor Gene In Vitro and In Vivo
- An X-linked NDI Mutation Reveals a Requirement for Cell Surface V2R Expression
- Angiotensin II AT1 Receptor Blockade Decreases Vasopressin-Induced Water Reabsorption and AQP2 Levels in NaCl-Restricted Rats
- Appropriate Polarization Following Pharmacological Rescue of V2 Vasopressin Receptors Encoded by X-Linked Nephrogenic Diabetes Insipidus Alleles Involves a Conformation of the Receptor That Also Attains Mature Glycosylation
- Aquaporins: From Physiology to Nephrogenic Diabetes Insipidus
- Bidirectional Regulation of AQP2 Trafficking and Recycling: Involvement of AQP2-S256 Phosphorylation
- Calcineurin-NFATc Signaling Pathway Regulates AQP2 Expression in Response to Calcium Signals and Osmotic Stress
- Characterization of an Aquaporin-2 Water Channel Gene Mutation Causing Partial Nephrogenic Diabetes Insipidus in a Mexican Family: Evidence of Increased Frequency of the Mutation in the Town of Origin
- Cloning of the Human Type-2 Vasopressin Receptor Gene
- Comparative Mapping on the Mouse and Human X Chromosomes of a Human cDNA Clone Encoding the Vasopressin Renal-Type Receptor (AVP2R)
- Compartmentalization of cAMP-Dependent Signaling by Phosphodiesterase-4D is Involved in the Regulation of Vasopressin-Mediated Water Reabsorption in Renal Principal Cells
- Constitutive and Regulated Membrane Expression of Aquaporin 1 and Aquaporin 2 Water Channels in Stably Transfected LLC-PK1 Epithelial Cells
- Cross Talk Between Stimulatory and Inhibitory Guanosine 5'-Triphosphate Binding Proteins: Role in Activation and Desensitization of the Adenylate Cyclase Response to Vasopressin
- Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway
- Defects of G Protein-Coupled Signal Transduction in Human Disease
- Desensitization of the Human V2 Vasopressin Receptor. Homologous Effects in the Absence of Heterologous Desensitization
- Desmopressin for Nocturnal Enuresis in Nephrogenic Diabetes Insipidus
- Development and Characterization of a Mouse Cell Line Expressing the Human V2 Vasopressin Receptor Gene
- Diabetes Insipidus (Robertson)
- Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
- Dual Actions of Vasopressin and Oxytocin in Regulation of Water Permeability in Terminal Collecting Duct
- Effect of an Acute Oral Ibuprofen Intake on Urinary Aquaporin-2 Excretion in Healthy Humans
- Effects of Arginine Vasopressin and 1-Desamino-8-D Arginine Vasopressin on Forearm Vasculature of Healthy Subjects and Patients with a V2 Receptor Defect
- Epinephrine and dDAVP Administration in Patients with Congenital Nephrogenic Diabetes Insipidus. Evidence for a pre-cyclic AMP V2 Receptor Defective Mechanism
- Evidence for Intact V1-vasopressin Receptors in Congenital Nephrogenic Diabetes Insipidus
- Expression Cloning of the Human V2 Vasopressin Receptor
- Familial Nephrogenic Diabetes Insipidus: Report of Two Families
- Fibrinolytic Responses to 1-desamino-8-D-arginine-vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- From Vasopressin Receptor to Water Channel: Intracellular Traffic, Constraint and By-pass
- Functional Characterization of Five V2 Vasopressin Receptor Gene Mutations
- Functional Involvement of VAMP/Synaptobrevin-2 in cAMP-Stimulated Aquaporin 2 Translocation in Renal Collecting Duct Cells
- Functional Rescue of Mutant V2 Vasopressin Receptors Causing Nephrogenic Diabetes Insipidus by a Co-Expressed Receptor Polypeptide
- Functional Rescue of Vasopressin V2 Receptor Mutants in MDCK Cells by Pharmacochaperones: Relevance to Therapy of Nephrogenic Diabetes Insipidus
- Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059
- Functional Role of the NPxxY Motif in Internalization of the Type 2 Vasopressin Receptor in LLC-PK1 Cells
- G-Protein-Coupled Receptors in Endocrine Disease
- G-Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity of G-Protein Recognition
- GS-Activating Receptors: Modes of Transmembrane Signalling and Genetic Defects
- Hemodynamic and Coagulation Responses to 1-desamino[8-D-arginine] Vasopressin in Patients with Congenital Nephrogenic Diabetes Insipidus
- Heteroligomerization of an Aquaporin-2 Mutant with Wild-Type Aquaporin-2 and Their Misrouting to Late Endosomes/Lysosomes Explains Dominant Nephrogenic Diabetes Insipidus
- Hypertonicity Regulates the Aquaporin-2 Promoter Independently of Arginine Vasopressin
- Hypokalemic Nephropathy and Nephrogenic Diabetes Insipidus Due to Excessive Consumption of a Soft Drink
- Identification of Rab3-, Rab5a- and Synaptobrevin II-like Proteins in a Preparation of Rat Kidney Vesicles Containing the Vasopressin-Regulated Water Channel
- Identification of a Multiprotein "Motor" Complex Binding to Water Channel Aquaporin-2
- Identification of a Novel A-kinase Anchoring Protein 18 Isoform and Evidence for its Role in the Vasopressin-induced Aquaporin-2 Shuttle in Renal Principal Cells
- In Vitro Micro-Autoradiography of Atrial Natriuretic Peptide in Biopsy Specimens from Patients with Renal Diseases
- Inborn Errors of Signal Transduction: Mutations in G Proteins and G Protein-coupled Receptors as a Cause of Disease
- Increased Renal Responsiveness to Vasopressin and Enhanced V2 Receptor Signaling in RGS2-/- Mice
- Indomethacin Enhances Shuttling of Aquaporin-2 Despite Decreased Abundance in Rat Kidney
- Inheritance of Mutations in the V2 Receptor Gene in Thirteen Families with Nephrogenic Diabetes Insipidus
- Inhibition of Endocytosis Causes Phosphorylation (S256)-Independent Plasma Membrane Accumulation of AQP-2
- Insulin Potentiates AVP-induced AQP2 Expression in Cultured Renal Collecting Duct Principal Cells
- Lithium-Induced Nephrogenic Diabetes Insipidus Treated with Indomethacin
- MAL Decreases the Internalization of the Aquaporin-2 Water Channel
- Maturation of Receptor Proteins in Eukaryotic Expression Systems
- Mechanism of Lithium-Induced Polyuria in the Rat
- Mechanisms and Regulation of Water Permeability in Renal Epithelia
- Mechanisms and Regulation of Water Transport in the Kidney
- Meniere's Disease in Congenital Nephrogenic Diabetes Insipidus: Report of Two Twins
- Methyl-β-Cyclodextrin Induces Vasopressin-Independent Apical Accumulation of Aquaporin-2 in the Isolated, Perfused Rat Kidney
- Molecular Biology of Diabetes Insipidus
- Molecular Cloning of the Receptor for Human Antidiuretic Hormone
- Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Molecular Mechanism of Water Channel Aquaporin-2 Trafficking
- Molecular Mechanisms for the Regulation of Water Transport in Amphibian Epithelia by Antidiuretic Hormone
- Molecular and Cellular Biology of Vasopressin and Oxytocin Receptors and Action in the Kidney
- Mutations and Diseases of G Protein Coupled Receptors
- Mutations in the V2 Vasopressin Receptor Gene are Associated with X-linked Nephrogenic Diabetes Insipidus
- Mutations in the Vasopressin V2 Receptor and Aquaporin-2 Genes in 12 Families with Congenital Nephrogenic Diabetes Insipidus
- N-ethylmaleimide (NEM) Causes Aquaporin-2 Trafficking in the Renal Inner Medullary Collecting Duct by Direct Activation of Protein Kinase A
- Nephrogenic Diabetes Insipidus (Bichet - November 1998)
- Nephrogenic Diabetes Insipidus Caused By Mutation of Tyr205: A Key Residue of V2 Vasopressin Receptor Function
- Nephrogenic Diabetes Insipidus Presenting After Head Trauma
- Normal Fibrinolytic Responses to 1-Desamino-8-D-Arginine Vasopressin in Patients with Nephrogenic Diabetes Insipidus Caused by Mutations in the Aquaporin 2 Gene
- Normal Hemodynamic and Coagulation Responses to 1-Diamino-8-D-Arginine Vasopressin in a Case of Lithium-Induced Nephrogenic Diabetes Insipidus. Results of Treatment by a Prostaglandin Synthesis Inhibitor (Indomethacin).
- Osmolality and Solute Composition are Strong Regulators of AQP2 Expression in Renal Principal Cells
- Oxytocin Induces Apical and Basolateral Redistribution of Aquaporin-2 in Rat Kidney
- Pathogenesis and Treatment of Autosomal-Dominant Nephrogenic Diabetes Insipidus Caused by an Aquaporin 2 Mutation
- Pharmacochaperones Post-Translationally Enhance Cell Surface Expression by Increasing Conformational Stability of Wild-Type and Mutant Vasopressin V2 Receptors
- Pharmacological Chaperones Rescue Cell-Surface Expression and Function of Misfolded V2 Vasopressin Receptor Mutants
- Phenotypes Developed in Secretin Receptor-Null Mice Indicated a Role for Secretin in Regulating Renal Water Reabsorption
- Phosphorylation of the V2 Vasopressin Receptor
- Possible Liposomal Amphotericin B-Induced Nephrogenic Diabetes Insipidus
- Prolongation of Antidiuretic Response to Desmopressin Acetate by Iontophoretic Transdermal Delivery in Rats
- Recent Advances in Water Transport
- Reconstitution of Mutant V2 Vasopressin Receptors by Adenovirus-mediated Gene Transfer
- Regulation of V2 Vasopressin Receptor Degradation by Agonist Promoted Ubiquitination
- Relationship Between Vasopressin-Sensitive Water Transport and Plasma Membrane Fluidity in Kidney Collecting Tubule
- Renal Aquaporins
- Reversed Polarized Delivery of an Aquaporin-2 Mutant Causes Dominant Nephrogenic Diabetes Insipidus
- Role of Aquaporin Water Channels in Kidney and Lung
- Role of Sodium Depletion in Acute Antidiuretic Effect of Bendroflumethiazide in Rats with Nephrogenic Diabetes Insipidus
- Short-Chain Ubiquitination Mediates the Regulated Endocytosis of the Aquaporin-2 Water Channel
- Stimulation of AQP2 Membrane Insertion in Renal Epithelial Cells In Vitro and In Vivo by the cGMP Phosphodiesterase Inhibitor Sildenafil Citrate (Viagra)
- The Aquaporin Family of Molecular Water Channels
- The C-Terminal Tail of Aquaporin-2 Determines Apical Trafficking
- The Effect of Eight V2 Vasopressin Receptor Mutations on Stimulation of Adenylyl Cyclase and Binding to Vasopressin
- The Ins and Outs of Aquaporin-2 Trafficking
- The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel
- Tonicity-Responsive Enhancer Binding Protein is an Essential Regulator of Aquaporin-2 Expression in Renal Collecting Duct Principal Cells
- Two Novel Mutations in the Aquaporin-2 and the Vasopressin V2 Receptor Genes in Patients with Congenital Nephrogenic Diabetes Insipidus
- Urea Transporter UT-A1 and Aquaporin-2 Proteins Decrease in Response to Angiotensin II or Norepinephrine-Induced Acute Hypertension
- Vasopressin Receptors in Health and Disease
- Vasopressin V2 Receptor Mutants that Cause X-linked Nephrogenic Diabetes Insipidus: Analysis of Expression, Processing, and Function
- Vasopressin and Oxytocin Receptors
- Vasopressin-Independent Renal Urinary Concentration: Increased rBSC1 and Enhanced Countercurrent Multiplication
- Vasopressin-Sensitive Adenylate Cyclase: Subunit Interactions Assessed by Target Analysis and Computer Modelling
- Water Channels
- Water Channels in Health and Disease
Used in 7 Proceeding abstracts
Used in 7 Proceeding abstracts
- Aquaporin-2 Expression in Primary Cultures of Rat Inner Medullary Collecting Duct Cells - A New In-Vitro Model System Facilitating the Study of the Vasopressin-Regulated Antidiuretic Machinery at the Cellular Level
- Pitfalls in the Differential Diagnosis of Nephrogenic Diabetes Insipidus.
- Purinergic Control of Medullary Collecting Duct Function: A Novel Vasopressin-independent Regulatory Mechanism
- Recycling of the V2 Vasopressin Receptor
- Structure-Function Analysis of the V2 Vasopressin Receptor
- V2 vasopressin receptor dysfunction in patients with nephrogenic diabetes insipidus is caused by different molecular mechanisms
- V2 vasopressin receptor-arrestin interactions
Used in 15 Proceeding translations
Used in 15 Proceeding translations
- Bartter syndrome with sensorineural deafness: molecular genetics
- Bypassing the vasopressin receptor in aquaporin 2 trafficking: from cell biology to potential therapy of nephrogenic diabetes insipidus
- Effects of Carbenoxolone on Sodium Transporter and Aquaporin-2 Abundance in Kidney
- Functional investigations of the vasopressin regulated antidiuretic machinery in single inner medullary collecting duct (IMCD) cells
- Hormone-regulated intrenalization of the vasopressin V2 receptor in a polarized renal collecting duct cell system
- Long- and Short-Term Regulation of AQP2 Expression and Function
- Mineralocorticoid receptor mediated ENaC and AQP2 regulation in rats with lithium-induced NDI
- Modulation of vasopressin-dependent AQP2 expression in cultured mpkCCDc14 collecting duct principal cells by aldosterone, insulin, and hypertonicity
- Protein Kinase C involvement in aquaporin-2 endocytosis in cell culture
- Recycling of the V2 Vasopressin Receptor
- Regulation of Aquaporin-2 trafficking by Vasopressin in Renal Collecting Duct: Roles of Ryanodine-Sensitive Ca2+ Stores and Calmodulin
- Transport Defects of V2 Receptor Mutants Found in Patients with X-linked Nephrogenic Diabetes Insipidus
- V2 vasopressin receptor mutants responsible for nephrogenic diabetes insipidus associate with the molecular chaperones calnexin and Hsp70
- Vasopressin-induced / cyclic AMP-mediated aquaporin 2 translocation is a Ca2+-independent, slow exocytotic process
- cDNA Array Analysis Identifies Vasopressin Regulation of 11 bHSD-2 in Rat Renal Collecting Duct
Used in 49 Term definitions
Used in 49 Term definitions
- 1-desamino-8-D-arginine vasopressin
- G-protein coupled receptors
- G-protein-coupled receptors
- acidophil
- adrenocorticotropic hormone
- angiotensin II
- atrial natriuretic peptide
- autocrine
- basophils
- bind
- binding
- binds
- blockade
- bound
- corticotropin
- end-organ resistance
- enteroendocrine cells
- epinephrine
- erythropoietin
- fever
- fibroblast growth hormone
- glucagon
- glucocorticoid
- hormonal
- hormone
- hormones
- hydrocortisone
- hypogonadotropic hypogonadism
- inducible
- insulin
- ligand
- ligands
- luteinizing hormone
- membrane protein
- messenger
- neurohormones
- neurophysins
- pancreatic polypeptide
- paracrine
- parathyroid hormone
- progestin
- releasing hormones
- secretin
- signal transduction
- target
- target cell
- thyroid gland
- thyrotropin
- vasopressin receptor
